Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TIF-IA).
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TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3pPhosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF.Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoterhRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promotersmTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityControl of rRNA transcription in Escherichia coliFunction of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoterAffinity purification of mammalian RNA polymerase I. Identification of an associated kinaseTor pathway regulates Rrn3p-dependent recruitment of yeast RNA polymerase I to the promoter but does not participate in alteration of the number of active genes.Basonuclin regulates a subset of ribosomal RNA genes in HaCaT cellsBiased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene.Identification of a novel 70 kDa protein that binds to the core promoter element and is essential for ribosomal DNA transcription.The role of c-myc in cellular growth control.Survey and summary: transcription by RNA polymerases I and III.A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcriptionWisely chosen paths--regulation of rRNA synthesis: delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden.A purified transcription factor (TIF-IB) binds to essential sequences of the mouse rDNA promoter.Transcription and tyranny in the nucleolus: the organization, activation, dominance and repression of ribosomal RNA genesIsolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I.Two complex regions, including a TATA sequence, are required for transcription by RNA polymerase I in Neurospora crassa.Factor C*, the specific initiation component of the mouse RNA polymerase I holoenzyme, is inactivated early in the transcription processIn vivo regulation of rRNA transcription occurs rapidly in nondividing and dividing Drosophila cells in response to a phorbol ester and serum.Inhibition of rRNA synthesis by poliovirus: specific inactivation of transcription factors.Ribosomal gene clusters are uniquely proportioned between open and closed chromatin structures in both tomato leaf cells and exponentially growing suspension cultures.Environmental signaling through the mechanistic target of rapamycin complex 1: mTORC1 goes nuclear.Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA.The core promoter of mouse rDNA consists of two functionally distinct domains.Purification of components required for accurate transcription of ribosomal RNA from Acanthamoeba castellanii.Regulation of ribosomal gene transcription.The yeast RNA polymerase I promoter: ribosomal DNA sequences involved in transcription initiation and complex formation in vitroPolymerase III transcription factor B activity is reduced in extracts of growth-restricted cellsFactors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex.Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity.TIF-IC, a factor involved in both transcription initiation and elongation of RNA polymerase I.Transcriptional enhancement by upstream activators is brought about by different molecular mechanisms for class I and II RNA polymerase genes.A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesisThe nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation.In vitro transcription of Drosophila rRNA genes shows stimulation by a phorbol ester and serum.The RNA polymerase I transcription factor UBF is the product of a primary response gene.
P2860
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P2860
Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TIF-IA).
description
1985 nî lūn-bûn
@nan
1985年の論文
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1985年学术文章
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1985年学术文章
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1985年学术文章
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1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
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1985年學術文章
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name
Growth-dependent regulation of ...... on initiation factor (TIF-IA).
@en
type
label
Growth-dependent regulation of ...... on initiation factor (TIF-IA).
@en
prefLabel
Growth-dependent regulation of ...... on initiation factor (TIF-IA).
@en
P2093
P2860
P356
P1476
Growth-dependent regulation of ...... on initiation factor (TIF-IA).
@en
P2093
D Buttgereit
G Pflugfelder
P2860
P304
P356
10.1093/NAR/13.22.8165
P577
1985-11-01T00:00:00Z