TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages.
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Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphataseCD40 in coronary artery disease: a matter of macrophages?Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophagesSuppression of antigen-specific CD4+ T cell activation by SRA/CD204 through reducing the immunostimulatory capability of antigen-presenting cellDeficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profileTumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans.CD40 is essential in the upregulation of TRAF proteins and NF-kappaB-dependent proinflammatory gene expression after arterial injurycIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligandCell penetrating peptide inhibitors of nuclear factor-kappa B.Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wallCD137 expression is induced by Epstein-Barr virus infection through LMP1 in T or NK cells and mediates survival promoting signals.Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling.Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes.CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells.TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.Different activation of TRAF4 and TRAF6 in inflammatory bowel diseaseCD40 controls CXCR5-induced recruitment of myeloid-derived suppressor cells to gastric cancerRoles of TRAF6 in CD40 signaling.CD40-CD40 ligand interactions in human microglia induce CXCL8 (interleukin-8) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator protein-1 (AP-1)The diverse functions of Src family kinases in macrophages.AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling.Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype.CD40 and the immune response to parasitic infections.Impact of the CD40-CD40L dyad in Alzheimer's diseaseSrc-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk.A CD40 Kozak sequence polymorphism and susceptibility to antibody-mediated autoimmune conditions: the role of CD40 tissue-specific expression.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells.Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40+ monocyte differentiation.Human trophoblast-derived exosomal fibronectin induces pro-inflammatory IL-1β production by macrophages.The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas.SOLUBLE CD40 LIGAND IN DEMENTIA.TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation.Survival analysis and microarray profiling identify Cd40 as a candidate for the Salmonella susceptibility locus, Ity5.Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes.Lactobacillus rhamnosus GG reduces hepatic TNFα production and inflammation in chronic alcohol-induced liver injury.The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.CD40, autophagy and Toxoplasma gondii.Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
P2860
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P2860
TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
TNF receptor-associated factor ...... in monocytes and macrophages.
@en
type
label
TNF receptor-associated factor ...... in monocytes and macrophages.
@en
prefLabel
TNF receptor-associated factor ...... in monocytes and macrophages.
@en
P2093
P1476
TNF receptor-associated factor ...... in monocytes and macrophages.
@en
P2093
Kimberly Z Head
Larry M Wahl
Lata Mukundan
Lihua Zhang
P304
P356
10.4049/JIMMUNOL.174.2.1081
P407
P577
2005-01-01T00:00:00Z