The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. - Wikidata - awgldk - TriplyDB

The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.

The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.

http://www.wikidata.org/entity/Q47245105

about

CD40 in coronary artery disease: a matter of macrophages?Noncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation The role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis.Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile CD40 signaling to the rescue: A CD8 exhaustion perspective in chronic infectious diseases CD40L and Its Receptors in Atherothrombosis-An Update Creating a Biomarker Panel for Early Detection of Chemotherapy Related Cardiac Dysfunction in Breast Cancer Patients The platelet as an immune cell-CD40 ligand and transfusion immunomodulation Tumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans.CD40 is essential in the upregulation of TRAF proteins and NF-kappaB-dependent proinflammatory gene expression after arterial injury Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomes.Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling.Crucial role of CD40 signaling in vascular wall cells in neointimal formation and vascular remodeling after vascular interventions Platelet PI3Kγ Contributes to Carotid Intima-Media Thickening under Severely Reduced Flow Conditions.CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells.Rosuvastatin Attenuates CD40L-Induced Downregulation of Extracellular Matrix Production in Human Aortic Smooth Muscle Cells via TRAF6-JNK-NF-κB Pathway.Circulating inflammatory cells are associated with vein graft stenosis Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals.Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response.Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.The CD40-CD40L system in cardiovascular disease.Inflammation and immune system interactions in atherosclerosis.Regulation of atherosclerotic plaque inflammation.Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype.Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells.Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury.The role of platelets in the pathogenesis of systemic sclerosis.Feeling the elephant of cardiovascular cell therapy.New frontiers for platelet CD154.CD40L controls obesity-associated vascular inflammation, oxidative stress and endothelial dysfunction in mice - translational aspects for man.CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction.Tumor necrosis factor receptor-associated factor 5 is an essential mediator of ischemic brain infarction.Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice.

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The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.

http://www.wikidata.org/entity/Q47245105

description

2008 nî lūn-bûn

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

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The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

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type

label

The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

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The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

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The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

@en

The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

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BLOOD-2007-05-088906

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The CD40-TRAF6 axis is the key ...... ation and arterial remodeling.

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Andrew C Newby

http://www.w3.org/2001/XMLSchema#string

Ben J Janssen

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Cory L Ahonen

http://www.w3.org/2001/XMLSchema#string

Dirk Lievens

http://www.w3.org/2001/XMLSchema#string

Erwin Wijnands

http://www.w3.org/2001/XMLSchema#string

Esther Lutgens

http://www.w3.org/2001/XMLSchema#string

Imke Munnix

http://www.w3.org/2001/XMLSchema#string

Jack Cleutjens

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Johan Heemskerk

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Linda Beckers

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P2860

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells.

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

CD40 signaling and plaque instability.

Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype.

Inflammation and restenosis: implications for therapy.

The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation

CD40 and its ligand in atherosclerosis.

CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

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4596-4604

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scholarly article

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10.1182/BLOOD-2007-05-088906

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9

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111

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Christian Weber

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2008-01-14T00:00:00Z

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5656633

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18195092

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5726330

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