Overproduction of VEGF concomitantly expressed with its receptors promotes growth and survival of melanoma cells through MAPK and PI3K signaling.
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Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesisVEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growthVascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1Cancer biomarker discovery: the entropic hallmark.Phase 2 trial of carboplatin, weekly paclitaxel, and biweekly bevacizumab in patients with unresectable stage IV melanoma: a North Central Cancer Treatment Group study, N047A.Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profilingTargeted therapy in melanoma.Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays.EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2.Therapy for metastatic melanoma: the past, present, and future.Comparison of growth factor signalling pathway utilisation in cultured normal melanocytes and melanoma cell lines.A review of novel therapies for melanoma.Vasculogenic mimicry of HT1080 tumour cells in vivo: critical role of HIF-1α-neuropilin-1 axis.Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth.Vemurafenib: an evidence-based review of its clinical utility in the treatment of metastatic melanomaExpression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib.Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction.Fructopyrano-(1→4)-glucopyranose inhibits the proliferation of liver cancer cells and angiogenesis in a VEGF/VEGFR dependent manner.Targeting angiogenesis in melanoma: prospects for the futureBRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor GrowthThe combination of axitinib followed by paclitaxel/carboplatin yields extended survival in advanced BRAF wild-type melanoma: results of a clinical/correlative prospective phase II clinical trial.Neuropilin-2: a novel biomarker for malignant melanoma?Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgraftsThe effect of bevacizumab on human malignant melanoma cells with functional VEGF/VEGFR2 autocrine and intracrine signaling loops.Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS.Melanocyte receptors: clinical implications and therapeutic relevance.Malignant melanoma in the 21st century: the emerging molecular landscape.Novel aspects of corneal angiogenic and lymphangiogenic privilege.Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding.Melanoma biomolecules: independently identified but functionally intertwined.WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis.The coming of ramucirumab in the landscape of anti-angiogenic drugs: potential clinical and translational perspectives.Inhibition of blood vessel formation in tumors by IL-18-polarized M1 macrophages.A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasion, angiogenesis and targets ERK1/2 phosphorylation.Targeting protein kinase-b3 (akt3) signaling in melanoma.Investigational drug MLN0128, a novel TORC1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models.Emerging growth factor receptor antagonists for the treatment of advanced melanoma.Thujone inhibits lung metastasis induced by B16F-10 melanoma cells in C57BL/6 mice.Effect of vegf gene knockdown on growth of the murine sarcoma cell line MS-K.Inhibition of activated receptor tyrosine kinases by Sunitinib induces growth arrest and sensitizes melanoma cells to Bortezomib by blocking Akt pathway.
P2860
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P2860
Overproduction of VEGF concomitantly expressed with its receptors promotes growth and survival of melanoma cells through MAPK and PI3K signaling.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Overproduction of VEGF concomi ...... rough MAPK and PI3K signaling.
@en
type
label
Overproduction of VEGF concomi ...... rough MAPK and PI3K signaling.
@en
prefLabel
Overproduction of VEGF concomi ...... rough MAPK and PI3K signaling.
@en
P2093
P1476
Overproduction of VEGF concomi ...... rough MAPK and PI3K signaling.
@en
P2093
Abelardo Moreno
Agnes Figueras
Ana Llorens
Angels Fabra
Antonia Vinyals
F Jesus Gonzalez
Joaquim Marcoval
Jordi Graells
P304
P356
10.1111/J.0022-202X.2004.23460.X
P407
P577
2004-12-01T00:00:00Z
P6179
1020761146