Nucleoside conformation is determined by the electronegativity of the sugar substituent.
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Crystal structure of an RNA aptamer bound to thrombinSynthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reactionThe 1.19 A X-ray structure of 2'-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor grooveConformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complexSolution structure of RNA duplexes containing alternating CG base pairs: NMR study of r(CGCGCG)2 and 2'-O-Me(CGCGCG)2 under low salt conditionsThermodynamics of 2'-ribose substitutions in UUCG tetraloopsInductive Effects on the Energetics of Prolyl Peptide Bond Isomerization: Implications for Collagen Folding and StabilityNovel 3'-ribonuclease and 3'-phosphatase activities of the bacterial non-homologous end-joining protein, DNA ligase DFit for the Eye: Aptamers in Ocular DisordersPrebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylationOligonucleotides containing 9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-adenine and -guanine: synthesis, hybridization and antisense properties.Approaches and strategies for the treatment of influenza virus infections.Intrinsic conformational properties of deoxyribonucleosides: implicated role for cytosine in the equilibrium among the A, B, and Z forms of DNAThermodynamic analysis of nylon nucleic acidsSelection and evolution of NTP-specific aptamers.Effects of oligonucleotide length and atomic composition on stimulation of the ATPase activity of translation initiation factor elF4A.Ribonucleotide-induced helical alteration in DNA prevents nucleosome formation2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA.Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic AgentsThermodynamic and structural characterization of 2'-nitrogen-modified RNA duplexes.The crystal and molecular structure of 2'-deoxy-2'-fluoroinosine monohydrate.The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer.Design, Synthesis, and Properties of Phosphoramidate 2',5'-Linked Branched RNA: Toward the Rational Design of Inhibitors of the RNA Lariat Debranching EnzymeFunction of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modificationsHigh-affinity and specific recognition of human thyroid stimulating hormone (hTSH) by in vitro-selected 2'-amino-modified RNA.The importance of fitting in: conformational preference of selenium 2' modifications in nucleosides and helical structures.2'-Fluoro modified nucleic acids: polymerase-directed synthesis, properties and stability to analysis by matrix-assisted laser desorption/ionization mass spectrometryChemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.Synthesis and structural characterization of 2'-fluoro-α-L-RNA-modified oligonucleotides.2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain.Investigation of catalysis by bacterial RNase P via LNA and other modifications at the scissile phosphodiester.Determination of the catalytic parameters of the N-terminal half of Escherichia coli ribonuclease E and the identification of critical functional groups in RNA substrates.Use of DNA, RNA, and chimeric templates by a viral RNA-dependent RNA polymerase: evolutionary implications for the transition from the RNA to the DNA world.Oligo-2'-fluoro-2'-deoxynucleotide N3'-->P5' phosphoramidates: synthesis and properties.Structural properties of DNA:RNA duplexes containing 2'-O-methyl and 2'-S-methyl substitutions: a molecular dynamics investigation.Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity.Differential stabilization by netropsin of inducible B-like conformations in deoxyribo-, ribo- and 2'-deoxy-2'-fluororibo-adenosine containing duplexes of (dA)n . (dT)n and (dA)n . (dU)na.Specific interaction of netropsin, distamycin-3 and analogs with LC duplexes: reversion towards the B form of the 2'-deoxy-.2'-deoxy-2'-fluoro-hybrid duplexes upon specific interaction with netropsin, distamycin-3 and analogs.Modified RNA sequence pools for in vitro selection.Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.
P2860
Q24652403-8EAABA1B-D279-4125-8F14-0CC08CEAD164Q25256550-85B32D8A-4717-4205-B1EF-51C1C1FD53D2Q27635370-14E76750-1DE5-43B1-85C7-D01EE9DAF4BFQ27663735-B467F504-346C-4F2C-95D3-47D1532EBABBQ27746939-CCD56176-23AC-44C8-8174-25CA03C8844CQ28352590-2AB38411-C268-475C-A0EB-990DC22671A4Q28468195-D7D93542-78E2-4836-AB9B-16DE2099C215Q28493015-0392E81D-BFB8-4D71-8F1F-7CF1CBEA1AA2Q28828283-5B165C11-F13A-4319-B746-3865E303754EQ30619518-D101D6BF-D294-4819-A5BD-A3133F7BE7B7Q31996937-C5D81DBC-9DB9-48B7-AEF1-C705583D0F37Q33730165-222FEEC2-F6F3-41B5-8FE3-09FE930390B2Q34170676-21243A34-B8DA-4362-ACE5-13F584C804D5Q34292250-F9D163C8-BBE1-49A6-961B-A9321CC293F0Q34353723-326D8D1B-FA03-46BB-95E2-BF644A20FF28Q34362106-06264ABB-0AE6-484E-98C2-747CFA334C33Q34599068-9348F539-410B-47AD-9BBE-0B53703007ADQ35197859-35BA117C-4C9C-4E18-99D3-BE4F1D0242FFQ35309726-9D1D93CC-5659-4F29-BA03-E9C9E22AEA36Q35618234-32916B81-2691-4B2A-B273-D26D785B72C1Q35737664-18B49635-1FCB-4895-AA50-8F42BDE53FF2Q36501439-033862A9-0C7A-40BF-8564-57A17166E8B2Q36567879-BDFA9BF1-FDD0-4F27-8360-3D14673CC21CQ36809670-3A3C674D-3415-4F20-9858-EAC1A167E03AQ36820144-666DDB26-2BA1-4FAF-96DC-6F106C17F722Q36855289-69BC0325-2081-478E-9C6C-1E26163A94F4Q36889550-64CCDFC8-E85A-4734-84C3-97FE04F86302Q38309810-02C22FED-B2A0-4815-94A9-865C912349D9Q38333758-A2637409-22AD-4672-AC60-F6C578C197C8Q38335060-10C58D57-2C54-410D-BB16-30F99A8EC1F0Q38350013-D26A6975-BE21-4EED-92A0-919E3293C061Q38350987-444A2145-0959-49FF-A4C3-6AAEA3BBB58EQ39595199-F7B6F7A9-A767-41C0-B8DF-427FAE34649EQ39717118-61CA7742-2A8C-4A37-8EDC-3DF1EA6B5DCCQ39728041-841190E5-E2F3-43DD-92A4-BBB206F53586Q40398102-70C11B70-A4CE-4CE1-836A-3FBF6EE16A70Q40463869-E68B0EF0-534F-4401-A71F-6414BBBACB30Q40466064-16E3AF83-4D0B-4F24-81F1-4242A5089E3AQ40523091-A4084FDA-1CA5-48FD-A526-5A9F9C665CF0Q40629852-82D52502-A395-4A8B-988A-DF2E4B2AF3C7
P2860
Nucleoside conformation is determined by the electronegativity of the sugar substituent.
description
1980 nî lūn-bûn
@nan
1980年の論文
@ja
1980年学术文章
@wuu
1980年学术文章
@zh-cn
1980年学术文章
@zh-hans
1980年学术文章
@zh-my
1980年学术文章
@zh-sg
1980年學術文章
@yue
1980年學術文章
@zh
1980年學術文章
@zh-hant
name
Nucleoside conformation is determined by the electronegativity of the sugar substituent.
@en
type
label
Nucleoside conformation is determined by the electronegativity of the sugar substituent.
@en
prefLabel
Nucleoside conformation is determined by the electronegativity of the sugar substituent.
@en
P2860
P356
P1476
Nucleoside conformation is determined by the electronegativity of the sugar substituent.
@en
P2093
Guschlbauer W
Jankowski K
P2860
P304
P356
10.1093/NAR/8.6.1421
P577
1980-03-01T00:00:00Z