Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling. - Wikidata - awgldk - TriplyDB

Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.

Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.

http://www.wikidata.org/entity/Q40481718

about

Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1 Nitrosothiol signaling in anoikis resistance and cancer metastasis MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis Roles of caveolin-1 on anoikis resistance in non small cell lung cancer Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1 Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival.Stress signaling and the shaping of the mammary tissue in development and cancer.Caveolin-1: a tumor-promoting role in human cancer.Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents.LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis.Elevated PI3K signaling drives multiple breast cancer subtypes.Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis?Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway Divergent control of Cav-1 expression in non-cancerous Li-Fraumeni syndrome and human cancer cell lines.Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.Gene expression profiling of circulating tumor cells and peripheral blood mononuclear cells from breast cancer patients.Lipid rafts and caveolae in signaling by growth factor receptors.Restoration of caveolin-1 expression suppresses growth and metastasis of head and neck squamous cell carcinoma.Caveolin-1: a marker for pancreatic cancer diagnosis.CpG island shore methylation regulates caveolin-1 expression in breast cancer Proteomic profiling of lipid rafts in a human breast cancer model of tumorigenic progression.The sensors and regulators of cell-matrix surveillance in anoikis resistance of tumors.Caveolins in rhabdomyosarcoma The role of caveolin-1 in human breast cancer.Integration of autophagy and anoikis resistance in solid tumors.Filamin A: Insights into its Exact Role in Cancers.The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines.Caveolin-1 regulates metastatic behaviors of anoikis resistant lung cancer cells.Elucidation of caveolin 1 both as a tumor suppressor and metastasis promoter in light of epigenetic modulators.Imperatorin sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells.Long-term hydrogen peroxide exposure potentiates anoikis resistance and anchorage-independent growth in lung carcinoma cells.WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells.Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity.The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility.Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis.

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Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.

http://www.wikidata.org/entity/Q40481718

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Caveolin-1 inhibits cell detac ...... tor-I receptors and signaling.

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Haim Werner

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Mordechai Liscovitch

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Sharon Maor

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P2860

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

Disruption of epithelial cell-matrix interactions induces apoptosis

Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury

A system for stable expression of short interfering RNAs in mammalian cells

Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor

Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors

Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

Anoikis mechanisms

Caveolin is an activator of insulin receptor signaling

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