Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
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GADD45 proteins: central players in tumorigenesisMelanoma differentiation-associated gene-7, MDA-7/IL-24, selectively induces growth suppression, apoptosis in human hepatocellular carcinoma cell line HepG2 by replication-incompetent adenovirus vector.Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.Oncolytic adenovirus SG600-IL24 selectively kills hepatocellular carcinoma cell lines.A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.Reversing translational suppression and induction of toxicity in pancreatic cancer cells using a chemoprevention gene therapy approachmda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Splice variants of mda-7/IL-24 differentially affect survival and induce apoptosis in U2OS cells.mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokineStrategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomasMolecular Mechanisms Governing IL-24 Gene Expression.Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic miceMelanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?Interferon-α enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma.Activation of ERK signaling and induction of colon cancer cell death by piperlongumine.Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities.mda-7/IL-24 Mediates Cancer Cell-Specific Death via Regulation of miR-221 and the Beclin-1 Axis.Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma.Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.Tumor growth inhibition of metastatic nasopharyngeal carcinoma cell lines by low dose of arsenic trioxide via alteration of cell cycle progression and induction of apoptosis.Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.Antioxidants tiron and N-acetyl-L-cysteine differentially mediate apoptosis in melanoma cells via a reactive oxygen species-independent NF-kappaB pathway.A combinatory use of adenoviruses expressing melanoma differentiation-associated gene-7 and replication-competent adenoviruses produces synergistic effects on pancreatic carcinoma cells.MDA-7/IL-24 inhibits cell survival by inducing apoptosis in nasopharyngeal carcinoma.Inhibition of angiogenesis by arsenic trioxide via TSP-1-TGF-β1-CTGF-VEGF functional module in rheumatoid arthritis.Cancer Terminator Viruses (CTV): A Better Solution for Viral-Based Therapy of Cancer.Lentivirus‑mediated MDA7/IL24 expression inhibits the proliferation of hepatocellular carcinoma cells.Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells.
P2860
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P2860
Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Induction of reactive oxygen s ...... to Ad.mda-7-induced apoptosis.
@en
type
label
Induction of reactive oxygen s ...... to Ad.mda-7-induced apoptosis.
@en
prefLabel
Induction of reactive oxygen s ...... to Ad.mda-7-induced apoptosis.
@en
P2093
P2860
P356
P1433
P1476
Induction of reactive oxygen s ...... to Ad.mda-7-induced apoptosis.
@en
P2093
Adly Yacoub
Devanand Sarkar
Irina V Lebedeva
Paul B Fisher
Rahul V Gopalkrishnan
Zao-Zhong Su
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208183
P407
P577
2005-01-01T00:00:00Z
P5875
P6179
1040180200