Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines. - Wikidata - awgldk - TriplyDB

Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines.

Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines.

http://www.wikidata.org/entity/Q40485825

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Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies Cullin-RING ubiquitin ligases: global regulation and activation cycles Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1 Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors Differential requirement for conserved tryptophans in human immunodeficiency virus type 1 Vif for the selective suppression of APOBEC3G and APOBEC3F.Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors HIV-1 Vif, APOBEC, and intrinsic immunity A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation 7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G Intracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification How Active Are Porcine Endogenous Retroviruses (PERVs)?The role of cullin 5-containing ubiquitin ligases Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB Host gene evolution traces the evolutionary history of ancient primate lentiviruses APOBEC3G: an intracellular centurion Multiple ways of targeting APOBEC3-virion infectivity factor interactions for anti-HIV-1 drug development.Molecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif.EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors.Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity.Vpr14-88-Apobec3G fusion protein is efficiently incorporated into Vif-positive HIV-1 particles and inhibits viral infection.Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex.APOBEC3G-depleted resting CD4+ T cells remain refractory to HIV1 infection.Identification of HIV-1 Vif regions required for CBF-β interaction and APOBEC3 suppression Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS.Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics.Identification of dominant negative human immunodeficiency virus type 1 Vif mutants that interfere with the functional inactivation of APOBEC3G by virus-encoded Vif Identification of 81LGxGxxIxW89 and 171EDRW174 domains from human immunodeficiency virus type 1 Vif that regulate APOBEC3G and APOBEC3F neutralizing activity.

P2860

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P2860

Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines.

http://www.wikidata.org/entity/Q40485825

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年学术文章

@wuu

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh

2004年學術文章

@zh-hant

name

Selective assembly of HIV-1 Vi ...... CS box and upstream cysteines.

@en

type

label

Selective assembly of HIV-1 Vi ...... CS box and upstream cysteines.

@en

prefLabel

Selective assembly of HIV-1 Vi ...... CS box and upstream cysteines.

@en

P1433

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Genes & Development

P1476

Selective assembly of HIV-1 Vi ...... CS box and upstream cysteines.

@en

P2093

Elana S Ehrlich

http://www.w3.org/2001/XMLSchema#string

Xianghui Yu

http://www.w3.org/2001/XMLSchema#string

Xiao-Fang Yu

http://www.w3.org/2001/XMLSchema#string

Yunkai Yu

http://www.w3.org/2001/XMLSchema#string

Zuoxiang Xiao

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

DNA deamination mediates innate immunity to retroviral infection

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

P304

2867-2872

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scholarly article

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10.1101/GAD.1250204

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23

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18

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2004-12-01T00:00:00Z

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8152251

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15574593

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534647

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