Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
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Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signalingRole of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis throughPerifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagyHypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathwaysThe novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5Maintaining glycogen synthase kinase-3 activity is critical for mTOR kinase inhibitors to inhibit cancer cell growth.The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translationCelastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors.Proteasome inhibitor PS-341 (bortezomib) induces calpain-dependent IkappaB(alpha) degradationPUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo5-allyl-7-gen-difluoromethoxychrysin enhances TRAIL-induced apoptosis in human lung carcinoma A549 cellsUsp9x- and Noxa-mediated Mcl-1 downregulation contributes to pemetrexed-induced apoptosis in human non-small-cell lung cancer cellsCelecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cellsProtein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells.ATBF1 inhibits estrogen receptor (ER) function by selectively competing with AIB1 for binding to the ER in ER-positive breast cancer cells.ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1Celecoxib-induced cytotoxic effect is potentiated by inhibition of autophagy in human urothelial carcinoma cells.Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms.Exposure to cyclooxygenase-2 inhibitors and risk of cancer: nested case-control studiesApoptotic effects of two COX-2 inhibitors on breast adenocarcinoma cells through COX-2 independent pathway.PDE5 inhibitors enhance celecoxib killing in multiple tumor types.DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer CellsAugmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagyThe NEDD8-activating enzyme inhibitor, MLN4924, cooperates with TRAIL to augment apoptosis through facilitating c-FLIP degradation in head and neck cancer cellsRictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.Cisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP.Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growthThe novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition.Combination of TRAIL and actinomycin D liposomes enhances antitumor effect in non-small cell lung cancer.Relationship between epidermal growth factor receptor (EGFR) mutation and serum cyclooxygenase-2 Level, and the synergistic effect of celecoxib and gefitinib on EGFR expression in non-small cell lung cancer cells.Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-X(L)/p53-mediated amplification mechanisms.Two COX-2 inhibitors induce apoptosis in human erythroleukemia K562cells by modulating NF-κB and FHC pathways.Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors.Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling.Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cellsDestruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain gliomaMethyl jasmonate induces apoptosis and pro-apoptotic autophagy via the ROS pathway in human non-small cell lung cancer
P2860
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P2860
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
@en
type
label
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
@en
prefLabel
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
@en
P2093
P2860
P356
P1476
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells
@en
P2093
Fadlo R Khuri
Shi-Yong Sun
Zhongmei Zhou
P2860
P304
P356
10.1093/JNCI/DJH322
P407
P50
P577
2004-12-01T00:00:00Z