Novel function of androgen receptor-associated protein 55/Hic-5 as a negative regulator of Smad3 signaling.
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Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticityNovel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activationPaxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS.Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment.VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells.Expression of oncogenic K-ras and loss of Smad4 cooperate to induce the expression of EGFR and to promote invasion of immortalized human pancreas ductal cells.Epithelial Hic-5/ARA55 expression contributes to prostate tumorigenesis and castrate responsiveness.Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.The diverse biofunctions of LIM domain proteins: determined by subcellular localization and protein-protein interaction.Hic-5, an adaptor-like nuclear receptor coactivator.The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways.Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway.Transforming growth factor-β1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin proteinAge-dependent renal cortical microvascular loss in female miceHic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/SrcDiverse roles for the paxillin family of proteins in cancer.CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic NeovesselsHic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulationAntagonistic regulation of cell-matrix adhesion by FosB and DeltaFosB/Delta2DeltaFosB encoded by alternatively spliced forms of fosB transcripts.The LIM domain protein nTRIP6 acts as a co-repressor for the transcription factor MEF2C in myoblasts.The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.Androgen receptor and growth factor signaling cross-talk in prostate cancer cells.Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression.HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription.Regulation of TGF-β Family Signaling by Inhibitory Smads.Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis.Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex.BRG1 in the Nucleus Accumbens Regulates Cocaine-Seeking Behavior.Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression.A Unique TGFB1-Driven Genomic Program Links Astrocytosis, Low-Grade Inflammation and Partial Demyelination in Spinal Cord Periplaques from Progressive Multiple Sclerosis Patients.Profiling Prostate Cancer Therapeutic Resistance.Mechanisms navigating the TGF-β pathway in prostate cancer.
P2860
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P2860
Novel function of androgen receptor-associated protein 55/Hic-5 as a negative regulator of Smad3 signaling.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
Novel function of androgen rec ...... regulator of Smad3 signaling.
@en
type
label
Novel function of androgen rec ...... regulator of Smad3 signaling.
@en
prefLabel
Novel function of androgen rec ...... regulator of Smad3 signaling.
@en
P2093
P356
P1476
Novel function of androgen rec ...... regulator of Smad3 signaling.
@en
P2093
David Danielpour
Kyung Song
Tracy L Sponseller
P304
P356
10.1074/JBC.M411575200
P407
P577
2004-11-23T00:00:00Z