Novel parathyroid hormone (PTH) antagonists that bind to the juxtamembrane portion of the PTH/PTH-related protein receptor.
about
Actions of the small molecule ligands SW106 and AH-3960 on the type-1 parathyroid hormone receptor.International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.Extra-long Gαs variant XLαs protein escapes activation-induced subcellular redistribution and is able to provide sustained signalingMechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformationsDiscovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probeNon-canonical signaling of the PTH receptorAltered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor.Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm.Heterologous downregulation of vasopressin type 2 receptor is induced by transferrinProlonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.Effects of the renal medullary pH and ionic environment on vasopressin binding and signalingIdentification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.PTH and Vitamin D.Design, conformational studies and analysis of structure-function relationships of PTH (1-11) analogues: the essential role of Val in position 2.Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor.Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1).
P2860
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P2860
Novel parathyroid hormone (PTH) antagonists that bind to the juxtamembrane portion of the PTH/PTH-related protein receptor.
description
2004 nî lūn-bûn
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name
Novel parathyroid hormone (PTH ...... /PTH-related protein receptor.
@en
type
label
Novel parathyroid hormone (PTH ...... /PTH-related protein receptor.
@en
prefLabel
Novel parathyroid hormone (PTH ...... /PTH-related protein receptor.
@en
P2093
P2860
P356
P1476
Novel parathyroid hormone (PTH ...... /PTH-related protein receptor.
@en
P2093
Ashok Khatri
Janet C Tsang
John T Potts
Naoto Shimizu
Thomas Dean
Thomas J Gardella
P2860
P304
P356
10.1074/JBC.M408270200
P407
P577
2004-11-17T00:00:00Z