PIASy-deficient mice display modest defects in IFN and Wnt signaling.
about
The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaBResolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalphaPIAS proteins: pleiotropic interactors associated with SUMORegulation of cytokine signaling pathways by PIAS proteinsInteractions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9.Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation.Interaction of moloney murine leukemia virus capsid with Ubc9 and PIASy mediates SUMO-1 addition required early in infection.Functional reconstitution of a tunable E3-dependent sumoylation pathway in Escherichia coli.SUMO--a post-translational modification with therapeutic potential?MafG sumoylation is required for active transcriptional repression.The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiationControl of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation.Dynamic expression of a LEF-EGFP Wnt reporter in mouse development and cancerSTAT3: a potential therapeutic target in dendritic cells for the induction of transplant tolerance.Emerging roles of the SUMO pathway in mitosisPIAS4 is associated with macro/microcephaly in the novel interstitial 19p13.3 microdeletion/microduplication syndrome.Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression.Novel initiation genes in squamous cell carcinomagenesis: a role for substrate-specific ubiquitylation in the control of cell survival.Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2.Biology and significance of the JAK/STAT signalling pathways.SUMO modification of DNA topoisomerase II: trying to get a CENse of it allDNA topoisomerase II and its growing repertoire of biological functions.How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway.Emerging roles of the SUMO pathway in development.SUMO rules: regulatory concepts and their implication in neurologic functions.Concepts and Methodologies to Study Protein SUMOylation: An Overview.Stat1 and SUMO modification.SUMO-1 modification of PIASy, an E3 ligase, is necessary for PIASy-dependent activation of Tcf-4.Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activityPIASγ expression in relation to clinicopathological, tumour factors and survival in indigenous black breast cancer women.Small ubiquitin-related modifier paralogs are indispensable but functionally redundant during early development of zebrafish.FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family.The conserved ancient role of chordate PIAS as a multilevel repressor of the NF-κB pathway.
P2860
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P2860
PIASy-deficient mice display modest defects in IFN and Wnt signaling.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
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name
PIASy-deficient mice display modest defects in IFN and Wnt signaling.
@en
type
label
PIASy-deficient mice display modest defects in IFN and Wnt signaling.
@en
prefLabel
PIASy-deficient mice display modest defects in IFN and Wnt signaling.
@en
P2093
P1476
PIASy-deficient mice display modest defects in IFN and Wnt signaling.
@en
P2093
Andrea Gilmozzi
Chris Turck
Claudio Sustmann
Denis Irmer
Elisabeth Kremmer
Matthias Kieslinger
Rudolf Grosschedl
P304
P356
10.4049/JIMMUNOL.173.10.6189
P407
P577
2004-11-01T00:00:00Z