Tyrosine phosphorylation of the LDL receptor-related protein (LRP) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation.
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ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophagesTissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expressionCTGF is increased in basal deposits and regulates matrix production through the ERK (p42/p44mapk) MAPK and the p38 MAPK signaling pathways.TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release.Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation.Connective tissue growth factor (CTGF/CCN2) is negatively regulated during neuron-glioblastoma interactionCTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasiaLRP-1: functions, signaling and implications in kidney and other diseases.Revisiting the matricellular concept.Connective-Tissue Growth Factor (CTGF/CCN2) Induces Astrogenesis and Fibronectin Expression of Embryonic Neural Cells In Vitro.The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis.Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signalingSmad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts.Regulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1.Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptorLDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studiesConnective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension.Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity.Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice.Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a AxisAngiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles.Fibronectin-based isolation of valve interstitial cell subpopulations: relevance to valve disease.Regulation of the composition of the extracellular matrix by low density lipoprotein receptor-related protein-1: activities based on regulation of mRNA expression.Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin.Carbon monoxide modulates alpha-smooth muscle actin and small proline rich-1a expression in fibrosisFocal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.CCN2: a master regulator of the genesis of bone and cartilage.Fell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the development of kidney fibrosis.An early history of CCN2/CTGF research: the road to CCN2 via hcs24, ctgf, ecogenin, and regenerin.The low density lipoprotein receptor-related protein functions as an endocytic receptor for decorin.
P2860
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P2860
Tyrosine phosphorylation of the LDL receptor-related protein (LRP) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Tyrosine phosphorylation of th ...... myofibroblast differentiation.
@en
type
label
Tyrosine phosphorylation of th ...... myofibroblast differentiation.
@en
prefLabel
Tyrosine phosphorylation of th ...... myofibroblast differentiation.
@en
P2093
P356
P1433
P1476
Tyrosine phosphorylation of th ...... myofibroblast differentiation.
@en
P2093
Dongxia Li
Haichang Huang
Haiyan Wang
P304
P356
10.1096/FJ.04-2357FJE
P407
P577
2004-10-06T00:00:00Z