The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain.
about
A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrinsStructure of an integrin with an αI domain, complement receptor type 4Structural basis of integrin regulation and signalingRequirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.Tests of the extension and deadbolt models of integrin activationIntegrin structures and conformational signalingMutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding.Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type.On the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation.
P2860
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P2860
The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The integrin alpha L beta 2 hy ...... regions to the I-like domain.
@en
type
label
The integrin alpha L beta 2 hy ...... regions to the I-like domain.
@en
prefLabel
The integrin alpha L beta 2 hy ...... regions to the I-like domain.
@en
P2093
P2860
P356
P1476
The integrin alpha L beta 2 hy ...... regions to the I-like domain.
@en
P2093
Emilia Tng
Ming Cheng
S K Alex Law
Suet-Mien Tan
P2860
P304
54334-54339
P356
10.1074/JBC.M407818200
P407
P577
2004-09-27T00:00:00Z