Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test.
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Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregatesThe epigenetic lorax: gene-environment interactions in human healthDifferentiation and selection of hepatocyte precursors in suspension spheroid culture of transgenic murine embryonic stem cellsThe use of in vitro data in risk assessment.Unrestricted somatic stem cells from human umbilical cord blood grow in serum-free medium as spheres.Embryotoxicity estimation of commonly used compounds with embryonic stem cell test.Present state and future perspectives of using pluripotent stem cells in toxicology researchInduced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery.Embryonic stem cells: An alternative approach to developmental toxicity testing.Drug discovery in Parkinson's disease-Update and developments in the use of cellular models.Potential application of embryonic stem cells in Parkinson's disease: drug screening and cell therapy.Human embryonic stem cells as a model for embryotoxicity screening.Assessment of Developmental Toxicants using Human Embryonic Stem Cells.Use of human embryonic stem cell-based models for male reproductive toxicity screening.Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation.Alternative models in developmental toxicology.Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain.Establishment of a molecular embryonic stem cell developmental toxicity assay.The embryonic stem cell test as tool to assess structure-dependent teratogenicity: the case of valproic acid.Human embryonic stem cell proliferation and differentiation as parameters to evaluate developmental toxicity.Specific effect of 5-fluorouracil on alpha-fetoprotein gene expression during the in vitro mouse embryonic stem cell differentiation.Optimization and Performance Assessment of the Chorion-Off [Dechorinated] Zebrafish Developmental Toxicity Assay.Non-human primate and rodent embryonic stem cells are differentially sensitive to embryotoxic compounds.Prospects and Frontiers of Stem Cell ToxicologyThe validated embryonic stem cell test to predict embryotoxicity in vitro.Use of In Vitro Morphogenesis of Mouse Embryoid Bodies to Assess Developmental Toxicity of Therapeutic Drugs Contraindicated in Pregnancy.A toxicology study to evaluate the embryotoxicity of metformin compared with the hypoglycemic drugs, the anticancer drug, the anti-epileptic drug, the antibiotic, and the cyclo-oxygenase (COX)-2 inhibitor.T-2 toxin induces apoptosis in differentiated murine embryonic stem cells through reactive oxygen species-mediated mitochondrial pathway.Alternatives to animal testing: current status and future perspectives.The limited application of stem cells in medicine: a review.A Developmental Toxicology Assay Platform for Screening Teratogenic Liability of Pharmaceutical Compounds.Evaluation of developmental toxicity using undifferentiated human embryonic stem cells.iPS Cells-The Triumphs and Tribulations.
P2860
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P2860
Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Improvement of an in vitro ste ...... the embryonic stem cell test.
@en
type
label
Improvement of an in vitro ste ...... the embryonic stem cell test.
@en
prefLabel
Improvement of an in vitro ste ...... the embryonic stem cell test.
@en
P2093
P1476
Improvement of an in vitro ste ...... the embryonic stem cell test.
@en
P2093
Andrea Seiler
Anke Visan
Elke Genschow
Horst Spielmann
Roland Buesen
P304
P356
10.1016/J.REPROTOX.2003.10.015
P577
2004-03-01T00:00:00Z