Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions.
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The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell deathSerotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporterThe plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter traffickingThe scaffolding protein PSD-95 interacts with the glycine transporter GLYT1 and impairs its internalizationProtein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.Missense dopamine transporter mutations associate with adult parkinsonism and ADHD.Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRETIdentification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD.Expression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6.Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters.Molecular mechanisms of SERT in platelets: regulation of plasma serotonin levels.MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II.Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulationConcentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D.SLC6 transporters: structure, function, regulation, disease association and therapeuticsRegulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease.The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo.Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding.Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathwayAttention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation.Making protein interactions druggable: targeting PDZ domains.The solute carrier 6 family of transportersA novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity.Membrane localization is critical for activation of the PICK1 BAR domain.A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporterNonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization.Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.Nicotinic receptor activation increases [3H]dopamine uptake and cell surface expression of dopamine transporters in rat prefrontal cortex.Trafficking of dopamine transporters in psychostimulant actions.Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization.Ctr9, a Protein in the Transcription Complex Paf1, Regulates Dopamine Transporter Activity at the Plasma Membrane.Calcium dependent interaction of calmodulin with the GlyT1 C-terminus.Single-quantum-dot tracking reveals altered membrane dynamics of an attention-deficit/hyperactivity-disorder-derived dopamine transporter coding variant.Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.C-terminal region regulates the functional expression of human noradrenaline transporter splice variants.Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization.A dopamine transporter mutation associated with bipolar affective disorder causes inhibition of transporter cell surface expression.Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.
P2860
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P2860
Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Surface targeting of the dopam ...... nical PDZ domain interactions.
@en
type
label
Surface targeting of the dopam ...... nical PDZ domain interactions.
@en
prefLabel
Surface targeting of the dopam ...... nical PDZ domain interactions.
@en
P2093
P50
P1476
Surface targeting of the dopam ...... onical PDZ domain interactions
@en
P2093
Christian Bjerggaard
Hanne Hastrup
Jacob U Fog
Kenneth Madsen
P304
P356
10.1523/JNEUROSCI.1863-04.2004
P407
P577
2004-08-01T00:00:00Z