about
Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMRA conserved salt bridge between transmembrane segments 1 and 10 constitutes an extracellular gate in the dopamine transporterNovel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein StabilisationMissense dopamine transporter mutations associate with adult parkinsonism and ADHD.Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter.Tandem facial amphiphiles for membrane protein stabilization.Mesitylene-Cored Glucoside Amphiphiles (MGAs) for Membrane Protein Studies: Importance of Alkyl Chain Density in Detergent Efficacy.Accessible Mannitol-Based Amphiphiles (MNAs) for Membrane Protein Solubilisation and StabilisationElucidation of structural elements for selectivity across monoamine transporters: novel 2-[(diphenylmethyl)sulfinyl]acetamide (modafinil) analoguesMaltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteinsMechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium SymportersMaltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study.Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter:sodium symporter.A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural StudyThe binding sites for benztropines and dopamine in the dopamine transporter overlap.Highly Branched Pentasaccharide-Bearing Amphiphiles for Membrane Protein Studies.Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter.Design and synthesis of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile (citalopram) analogues as novel probes for the serotonin transporter S1 and S2 binding sites.Novel tripod amphiphiles for membrane protein analysis.Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region.The use of LeuT as a model in elucidating binding sites for substrates and inhibitors in neurotransmitter transporters.Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the 5-HT transporterAn intracellular interaction network regulates conformational transitions in the dopamine transporter.Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions.N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization.Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites.Engineered Zn(2+) switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents.Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter.Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.Isomeric Detergent Comparison for Membrane Protein Stability: Importance of Inter-Alkyl-Chain Distance and Alkyl Chain Length.New penta-saccharide-bearing tripod amphiphiles for membrane protein structure studies.Resorcinarene-Based Facial Glycosides: Implication of Detergent Flexibility on Membrane-Protein Stability.Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study.Vitamin E-based glycoside amphiphiles for membrane protein structural studies.Steroid-based amphiphiles for membrane protein study: Importance of alkyl spacer for protein stability.A virtual high-throughput screening approach to the discovery of novel inhibitors of the bacterial leucine transporter, LeuT.
P50
Q28818343-67D36E77-B69D-4BE1-B211-C7363B01517DQ30368030-11369A4F-D7DD-442A-A152-EBD7FB04131AQ30374996-4551339E-9FC4-4CA9-BB9B-4820B4EF90EEQ30581669-8E5AAADD-A611-400C-9B3D-45CA0362AE9BQ33227640-225C8232-E10F-4120-9495-809E5968B654Q33738010-2835B9E3-C3B0-4D38-8DA7-62D880E7D24DQ33880152-8B2E6B5C-BBDD-42AE-AB7C-B3DDE90CC4EEQ33880255-1A222BCE-AC11-4D35-BAAB-8A8437B29475Q34402198-B0B55FAB-BBB0-4796-8A04-8D7B9291C36BQ34712509-0FED7B3D-DB75-4965-B3F7-0E4ABEB15AF0Q35662335-1F659D3A-3D84-4A41-9D8C-6ECC2B426DE5Q35836349-89D11142-67ED-4C0B-803B-D8D79BF5D022Q36283737-4D9C6B06-769C-4FC6-9AED-6FF1CE668B37Q36384637-CFD075E5-E098-4495-A23E-3F4738204F30Q36628365-069C0E77-6559-475F-A8B9-D02D9E57E9A1Q36813169-802851E6-EACF-4E28-BC61-1BE4D95A4C06Q36990361-7993B94E-0884-4EFE-B3CB-6A930231E3C8Q37001789-267D5DBF-4D76-4A3C-8DF4-82105D8981F7Q37315212-627F40C9-3EF4-4F97-BFC3-8BC5EB248EA9Q37490255-46B35DEF-7E04-46BD-90AA-D9F2499F01CDQ37626522-940114DE-7865-4FF6-B065-A492E83CD5BFQ37725017-FF6CF07C-33BF-4DAA-8612-88FA9DD21FD4Q38207434-83FD2026-61EC-486B-A088-126C2B79D029Q38572969-F7F6BA08-1252-4AEC-B996-9A7D26CD91D9Q39142337-C270CF77-5153-40A6-9D42-5863D2BD4F01Q40528317-65A5D9D7-ACA0-4181-BAEA-6E4D0803190AQ40685824-05C733E9-027A-4DE5-8013-6B92E46E2660Q43611923-86E3FE52-1733-4D9D-910B-79F0DA53DE86Q43723442-26520CDE-D29C-40A4-B376-05EAD468B6E8Q44457872-FE0F86DD-4F2E-450C-B6D4-DD8A253783D1Q44642043-F8C88FBE-3729-434D-B7B1-B3F729EF3F9EQ47163479-99D36394-5128-4EC0-967E-9427847860CDQ47797929-9554EDE3-465E-40A8-96C4-704C4C7E0165Q48112356-1FF61CB1-9383-43AC-A9A8-3981BDA4347CQ48183674-0DDBAE3A-E49A-4506-BEFF-9B850CD5AB5FQ51427234-15B486BB-9050-43B9-B0B9-0E3AAF8F4FD2Q52331632-2D3D8C60-B8F5-48E3-A99C-F08A3E5BE534Q52346929-FD2B5C43-0D95-49E9-A905-E95B8D9ABC18Q52585354-CEB46A3D-A1AE-4A54-9906-7AE9D2D8321AQ52842709-A0F1A8E1-3E5B-413E-A4F4-E96326FE06CF
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Claus J Loland
@ast
Claus J Loland
@en
Claus J Loland
@es
Claus J Loland
@nl
Claus J Loland
@sl
type
label
Claus J Loland
@ast
Claus J Loland
@en
Claus J Loland
@es
Claus J Loland
@nl
Claus J Loland
@sl
altLabel
Claus Juul Løland
@en
prefLabel
Claus J Loland
@ast
Claus J Loland
@en
Claus J Loland
@es
Claus J Loland
@nl
Claus J Loland
@sl
P1053
E-5975-2014
P106
P21
P31
P496
0000-0002-1773-1446