Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.
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Low-dose curcumin stimulates proliferation, migration and phagocytic activity of olfactory ensheathing cellsIn vivo and in vitro suppression of hepatocellular carcinoma by EF24, a curcumin analogCLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.Antimutagenic potential of curcumin on chromosomal aberrations in Allium cepaBiological activities of curcuminoids, other biomolecules from turmeric and their derivatives - A review.Structure based comprehensive modelling, spatial fingerprints mapping and ADME screening of curcumin analogues as novel ALR2 inhibitors.Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cellsLiver S9 Fraction-Derived Metabolites of Curcumin Analogue UBS109.Iron and cancer: more ore to be mined.Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cellsThiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells.Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts.Diphenyl difluoroketone: a potent chemotherapy candidate for human hepatocellular carcinomaHemorrhage-induced interleukin-1 receptor pathway in lung is suppressed by 3,5-bis(2-fluorobenzylidene)-4-piperidone in a rat model of hypovolemic shockAutophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog.Synthesis and evaluation of bisbenzylidenedioxotetrahydrothiopranones as activators of endoplasmic reticulum (ER) stress signaling pathways and apoptotic cell death in acute promyelocytic leukemic cells.Curcumin in cell death processes: a challenge for CAM of age-related pathologies.Curcumin: from ancient medicine to current clinical trials.Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases.Novel synthetic monoketone transmute radiation-triggered NFκB-dependent TNFα cross-signaling feedback maintained NFκB and favors neuroblastoma regression.The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress.Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs).The salutary effects of diphenyldifluoroketone EF24 in liver of a rat hemorrhagic shock modelNitrosative stress-induced Parkinsonian Lewy-like aggregates prevented through polyphenolic phytochemical analog interventionPotential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.Mouse pharmacokinetics and metabolism of the curcumin analog, 4-piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993).3,5-bis(2,4-difluorobenzylidene)-4-piperidone, a novel compound that affects pancreatic cancer growth and angiogenesisAnticancer activity of an imageable curcuminoid 1-[2-aminoethyl-(6-hydrazinopyridine-3-carbamidyl)-3,5-bis-(2-fluorobenzylidene)-4-piperidone (EFAH)The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells.EF24 suppresses maturation and inflammatory response in dendritic cells.Diphenyldifluoroketone EF24 Suppresses Pro-inflammatory Interleukin-1 receptor 1 and Toll-like Receptor 4 in lipopolysaccharide-stimulated dendritic cellsEF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expressionCurcumin derivative C817 inhibits proliferation of imatinib-resistant chronic myeloid leukemia cells with wild-type or mutant Bcr-Abl in vitro.Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.Combination of tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen speciesDehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents.Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogsActivation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategyEF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1.Pyridine analogues of curcumin exhibit high activity for inhibiting CWR-22Rv1 human prostate cancer cell growth and androgen receptor activation.
P2860
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P2860
Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Synthesis and biological evalu ...... and anti-angiogenesis agents.
@en
type
label
Synthesis and biological evalu ...... and anti-angiogenesis agents.
@en
prefLabel
Synthesis and biological evalu ...... and anti-angiogenesis agents.
@en
P2093
P1476
Synthesis and biological evalu ...... and anti-angiogenesis agents.
@en
P2093
Brian K Adams
Dennis C Liotta
Edward A Sausville
Eva M Ferstl
Frederick R Rickles
Gurmeet Kaur
James P Snyder
Mamoru Shoji
Marike Herold
Matthew C Davis
P304
P356
10.1016/J.BMC.2004.05.006
P407
P577
2004-07-01T00:00:00Z