FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells.
about
PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasiasMeclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasiaFGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescenceNF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cellsFibroblast growth factor 2 causes G2/M cell cycle arrest in ras-driven tumor cells through a Src-dependent pathway.Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilageHigh expression of p16INK4a and low expression of Bmi1 are associated with endothelial cellular senescence in the human cornea.Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formationMitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.The impact of polyphenols on chondrocyte growth and survival: a preliminary reportCell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP.Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme.Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytesNew insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders.Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin.Heparan sulfation is essential for the prevention of cellular senescence.Molecular pathology of the fibroblast growth factor family.Phosphoproteomics of Fibroblast Growth Factor 1 (FGF1) Signaling in Chondrocytes: Identifying the Signature of Inhibitory Response.FGF2 regulates proliferation, migration, and invasion of ECA109 cells through PI3K/Akt signalling pathway in vitro.FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G₂arrest in RCS chondrocytes.Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins.Fibroblast growth factor receptor 3 (FGFR3) is a strong heat shock protein 90 (Hsp90) client: implications for therapeutic manipulation.β2-adrenergic receptors inhibit the expression of collagen type II in growth plate chondrocytes by stimulating the AP-1 factor Jun-B.Instability restricts signaling of multiple fibroblast growth factors.Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.Fibroblast growth factor 2 involved in the pathogenesis of synovial chondromatosis of temporomandibular joint.
P2860
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P2860
FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells.
@en
type
label
FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells.
@en
prefLabel
FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells.
@en
P2093
P1476
FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells.
@en
P2093
Jiri Pachernik
Pavel Krejci
Pertchoui Mekikian
Robert Pogue
Vitezslav Bryja
William R Wilcox
P304
P356
10.1016/J.YEXCR.2004.03.011
P407
P50
P577
2004-07-01T00:00:00Z