Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.
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PCNA-MutSalpha-mediated binding of MutLalpha to replicative DNA with mismatched bases to induce apoptosis in human cellsAtl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O6-AlkylguaninesStructural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activitiesFluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug ResponseMismatch repair proteins are activators of toxic responses to chromium-DNA damage.Genomic and epigenetic instability in colorectal cancer pathogenesis.Comparative genomic analyses identify common molecular pathways modulated upon exposure to low doses of arsenic and cadmiumRepair of endogenous DNA base lesions modulate lifespan in miceAlkyltransferase-like protein (eATL) prevents mismatch repair-mediated toxicity induced by O6-alkylguanine adducts in Escherichia coli.CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage responseO6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation.Phosphorylated hMSH6: DNA mismatch versus DNA damage recognition.Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication forkp50 (NF-κB1) is an effector protein in the cytotoxic response to DNA methylation damageUndetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels.Structure and function of the components of the human DNA mismatch repair system.DNA mismatch repair and the DNA damage response.Beta clamp directs localization of mismatch repair in Bacillus subtilisBalancing repair and tolerance of DNA damage caused by alkylating agentsDecoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells.Chemotherapeutic implications in microsatellite unstable colorectal cancer.Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment.MGMT: a personal perspective.Genomic predictors of interindividual differences in response to DNA damaging agentsO6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling.Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.Prolonged cell cycle response of HeLa cells to low-level alkylation exposure.MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.Molecular status of pituitary carcinoma and atypical adenoma that contributes the effectiveness of temozolomide.MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine.NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair.Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.Acute dosing and p53-deficiency promote cellular sensitivity to DNA methylating agents.Cyclin E and histone H3 levels are regulated by 5-fluorouracil in a DNA mismatch repair-dependent manner.MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea.Single-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes.DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
P2860
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P2860
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.
@en
type
label
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.
@en
prefLabel
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.
@en
P1433
P1476
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine
@en
P2093
Leona D Samson
P304
P356
10.1016/S1097-2765(04)00162-5
P577
2004-04-01T00:00:00Z