Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells.
about
Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosisAutophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy.Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice.The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response.Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells.Granzyme A activates another way to dieDeath by a thousand cuts: granzyme pathways of programmed cell deathGranzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosisIntracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.Radiation-induced autophagy potentiates immunotherapy of cancer via up-regulation of mannose 6-phosphate receptor on tumor cells in mice.Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis.Mechanisms of granule-dependent killing.Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules.Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer.Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer.Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases.Gamma/delta intraepithelial lymphocytes in the mouse small intestine.Cell binding, internalization and cytotoxic activity of human granzyme B expressed in the yeast Pichia pastoris.Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.Mannose 6-phosphorylated proteins are required for tumor necrosis factor-induced apoptosis: defective response in I-cell disease fibroblasts.Immunological Properties of Murine Parthenogenetic Stem Cells and Their Differentiation ProductsGranzyme B-dependent and perforin-independent DNA fragmentation in intestinal epithelial cells induced by anti-CD3 mAb-activated intra-epithelial lymphocytes.A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
P2860
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P2860
Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Granzyme-mediated cytotoxicity ...... ate receptors on target cells.
@en
type
label
Granzyme-mediated cytotoxicity ...... ate receptors on target cells.
@en
prefLabel
Granzyme-mediated cytotoxicity ...... ate receptors on target cells.
@en
P2093
P2860
P50
P356
P1476
Granzyme-mediated cytotoxicity ...... ate receptors on target cells.
@en
P2093
Christopher J Froelich
Eberhard Günther
Srikumar M Raja
Stefan Höning
P2860
P304
20200-20210
P356
10.1074/JBC.M313108200
P407
P577
2004-02-25T00:00:00Z