Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels.
about
A novel class of ligand-gated ion channel is activated by Zn2+ZnT-3, a putative transporter of zinc into synaptic vesiclesElimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 geneSelective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zincTwo gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptorsInteraction of H+ and Zn2+ on recombinant and native rat neuronal GABAA receptorsMolecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptorsNutrient-gene interactions: a single nutrient and hundreds of target genes.Hippocampal zinc infusion delays the development of afterdischarges and seizures in a kindling model of epilepsyZinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicityCitrate modulates the regulation by Zn2+ of N-methyl-D-aspartate receptor-mediated channel current and neurotransmitter releaseZinc: indications in brain disorders.Chronic treatment with zinc and antidepressants induces enhancement of presynaptic/extracellular zinc concentration in the rat prefrontal cortexHow does zinc supplementation benefit anorexia nervosa?Zinc modulation of glycine receptorsModulation of glycine receptors in retinal ganglion cells by zinc.Metal impurities cause false positives in high-throughput screening campaignsZinc-permeable ion channels: effects on intracellular zinc dynamics and potential physiological/pathophysiological significance.Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology.Inhibition by Zn2+ of uridine 5'-triphosphate-induced Ca(2+)-influx but not Ca(2+)-mobilization in rat phaeochromocytoma cellsZn2+ ions: modulators of excitatory and inhibitory synaptic activity.Cysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition.Inhibition of human acid-sensing ion channel 1b by zincAbsence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer's disease neuropathology.Importance of zinc in the elderly: the ZENITH study.Probing the structural basis of Zn2+ regulation of the epithelial Na+ channel.Zinc Modulates Nanosilver-Induced Toxicity in Primary Neuronal Cultures.Zinc-mediated feedback at the synaptic terminals of vertebrate photoreceptors.Zinc in the central nervous system: From molecules to behavior.Zinc Selectively Blocks Neurosteroid-Sensitive Extrasynaptic δGABAA Receptors in the Hippocampus.Molecular mechanism of Zn2+ inhibition of a voltage-gated proton channelBipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses.Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS.In vitro protection by pyruvate against cadmium-induced cytotoxicity in hippocampal HT-22 cells.Zinc-induced modulation of SRSF6 activity alters Bim splicing to promote generation of the most potent apoptotic isoform BimS.A highly selective and sensitive in vivo fluorosensor for zinc(II) without cytotoxicity.Interaction between copper and zinc at GABA(A) receptors in acutely isolated cerebellar Purkinje cells of the rat.The inorganic perspective of nerve growth factor: interactions of Cu2+ and Zn2+ with the N-terminus fragment of nerve growth factor encompassing the recognition domain of the TrkA receptor.Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity.Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition.
P2860
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P2860
Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels.
@en
type
label
Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels.
@en
prefLabel
Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels.
@en
P1433
P1476
Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels.
@en
P2093
Harrison NL
P304
P356
10.1016/0028-3908(94)90152-X
P577
1994-08-01T00:00:00Z