CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A.
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CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and DiseaseThrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cellsThe CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implicationsTherapeutic opportunities for targeting the ubiquitous cell surface receptor CD47Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signalingActivated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its managementNeurovascular effects of CD47 signaling: promotion of cell death, inflammation, and suppression of angiogenesis in brain endothelial cells in vitroCD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interestCD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humansThrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration.Coexpression and coregulation analysis of time-series gene expression data in estrogen-induced breast cancer cellIdentification of a novel pathway that selectively modulates apoptosis of breast cancer cells.ABCG2, a novel antigen to sort luminal progenitors of BRCA1- breast cancer cells.Prolactin receptor-integrin cross-talk mediated by SIRPα in breast cancer cells.Thrombospondin-1-derived 4N1K peptide expression is negatively associated with malignant aggressiveness and prognosis in urothelial carcinoma of the upper urinary tract.Role of oxidative stress and caspase 3 in CD47-mediated neuronal cell deathTxr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes.Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosisBreast cancer stem cells, cytokine networks, and the tumor microenvironment.Nanoparticle-induced intraperitoneal hyperthermia and targeted photoablation in treating ovarian cancer.Lewis Y antigen modified CD47 is an independent risk factor for poor prognosis and promotes early ovarian cancer metastasisTherapeutic Targeting of CD47 to Modulate Tissue Responses to Ischemia and Radiation.Original insights on thrombospondin-1-related antireceptor strategies in cancer.Identification of TAX2 peptide as a new unpredicted anti-cancer agent.CD47 deficiency confers cell and tissue radioprotection by activation of autophagy.Differential effects of ABT-510 and a CD36-binding peptide derived from the type 1 repeats of thrombospondin-1 on fatty acid uptake, nitric oxide signaling, and caspase activation in vascular cells.CD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro model.CD47-retargeted oncolytic adenovirus armed with melanoma differentiation-associated gene-7/interleukin-24 suppresses in vivo leukemia cell growthCaspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton.Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis.Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapiesMyeloid Cell Origins, Differentiation, and Clinical Implications.Thrombospondin-1/CD47 blockade following ischemia-reperfusion injury is tissue protective.Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypesIs CD47 an innate immune checkpoint for tumor evasion?Thrombospondin-1 in urological cancer: pathological role, clinical significance, and therapeutic prospects.CD47: a potential immunotherapy target for eliminating cancer cells.Beta-adrenergic signaling promotes tumor angiogenesis and prostate cancer progression through HDAC2-mediated suppression of thrombospondin-1.Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action.An armed oncolytic herpes simplex virus expressing thrombospondin-1 has an enhanced in vivo antitumor effect against human gastric cancer.
P2860
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P2860
CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
CD47 mediates killing of breas ...... nhibition of protein kinase A.
@en
type
label
CD47 mediates killing of breas ...... nhibition of protein kinase A.
@en
prefLabel
CD47 mediates killing of breas ...... nhibition of protein kinase A.
@en
P1433
P1476
CD47 mediates killing of breas ...... nhibition of protein kinase A.
@en
P2093
William A Frazier
P304
P356
10.1158/0008-5472.CAN-03-1708
P407
P577
2004-02-01T00:00:00Z