ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing.
about
Mesenchymal Stromal Cells Can Regulate the Immune Response in the Tumor MicroenvironmentIncreasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognitionClinical implications of compounds designed to inhibit ECM-modifying metalloproteinases.Zoledronate can induce colorectal cancer microenvironment expressing BTN3A1 to stimulate effector γδ T cells with antitumor activity.The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation.How to Hit Mesenchymal Stromal Cells and Make the Tumor Microenvironment Immunostimulant Rather Than Immunosuppressive.Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells.Soluble NKG2D ligands limit the efficacy of immune checkpoint blockade.Targeting the Epidermal Growth Factor Receptor Can Counteract the Inhibition of Natural Killer Cell Function Exerted by Colorectal Tumor-Associated Fibroblasts.Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype.NKG2D Ligands-Critical Targets for Cancer Immune Escape and Therapy
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P2860
ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
ADAM10 new selective inhibitor ...... lls to NKG2D-mediated killing.
@en
type
label
ADAM10 new selective inhibitor ...... lls to NKG2D-mediated killing.
@en
prefLabel
ADAM10 new selective inhibitor ...... lls to NKG2D-mediated killing.
@en
P2093
P2860
P50
P1433
P1476
ADAM10 new selective inhibitor ...... lls to NKG2D-mediated killing.
@en
P2093
Alessandra Musso
Francesca Tosetti
Irene Dapino
Roberta Venè
P2860
P304
P356
10.1080/2162402X.2015.1123367
P577
2015-12-29T00:00:00Z