DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.
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Evidence for OTUD-6B participation in B lymphocytes cell cycle after cytokine stimulationThe deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.USP17 regulates Ras activation and cell proliferation by blocking RCE1 activityLys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activityEmbryonic demise caused by targeted disruption of a cysteine protease Dub-2USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor γt (RORγt) in Th17 cellsHyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity.DUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT ProteinsThe deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D).Ubiquitylation in normal and malignant hematopoiesis: novel therapeutic targets.Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.Steady-state kinetic studies reveal that the anti-cancer target Ubiquitin-Specific Protease 17 (USP17) is a highly efficient deubiquitinating enzyme.Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function.USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11.Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17.The regulation of snail: on the ubiquitin edge.Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis.Potential role of ZEB1 as a DNA repair regulator in colorectal cancer cells revealed by cancer-associated promoter profiling.Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis.USP17 is upregulated in osteosarcoma and promotes cell proliferation, metastasis, and epithelial-mesenchymal transition through stabilizing SMAD4.
P2860
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P2860
DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.
@en
type
label
DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.
@en
prefLabel
DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.
@en
P2093
P2860
P356
P1476
DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation
@en
P2093
Anne Rascle
James A Johnston
James F Burrows
Martine Humbert
Michael J McGrattan
P2860
P304
13993-14000
P356
10.1074/JBC.M311291200
P407
P577
2003-12-29T00:00:00Z