A role for the internal repeat of the Kaposi's sarcoma-associated herpesvirus latent nuclear antigen in the persistence of an episomal viral genome.
about
Kaposi's Sarcoma Herpesvirus Genome PersistenceComplex alternative cytoplasmic protein isoforms of the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 generated through noncanonical translation initiation.Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latencyCytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGASIdentification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistenceKaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen: Replicating and Shielding Viral DNA during Viral Persistence.Kaposi sarcoma herpesvirus pathogenesis.
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P2860
A role for the internal repeat of the Kaposi's sarcoma-associated herpesvirus latent nuclear antigen in the persistence of an episomal viral genome.
description
2011 nî lūn-bûn
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
A role for the internal repeat ...... e of an episomal viral genome.
@en
type
label
A role for the internal repeat ...... e of an episomal viral genome.
@en
prefLabel
A role for the internal repeat ...... e of an episomal viral genome.
@en
P2860
P356
P1433
P1476
A role for the internal repeat ...... e of an episomal viral genome.
@en
P2093
Khaled R Alkharsah
Thomas F Schulz
P2860
P304
P356
10.1128/JVI.06029-11
P407
P577
2011-11-16T00:00:00Z