A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.
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Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman PrimatesElicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV's Envelope Protein on Viral Replication in Cell CultureIdentification and specificity of broadly neutralizing antibodies against HIVStructural principles controlling HIV envelope glycosylation.How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design.Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer.Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope.Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys.What Are the Most Powerful Immunogen Design Vaccine Strategies? Reverse Vaccinology 2.0 Shows Great Promise.HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.HIV transmitted/founder vaccines elicit autologous tier 2 neutralizing antibodies for the CD4 binding siteProtection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail.Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.Development of a Preventive HIV Vaccine Requires Solving Inverse Problems Which Is Unattainable by Rational Vaccine Design.Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane.The glycan-mediated mechanism on the interactions of gp120 with CD4 and antibody: Insights from molecular dynamics simulation.Synthetic Three-Component HIV-1 V3 Glycopeptide Immunogens Induce Glycan-Dependent Antibody Responses.Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire.Global site-specific analysis of glycoprotein N-glycan processing.Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.Production of complex viral glycoproteins in plants as vaccine immunogensStabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodiesStructural Insights from HIV-Antibody Coevolution and Related Immunization StudiesProtein design: from computer models to artificial intelligenceRational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope TrimersDifferential processing of HIV envelope glycans on the virus and soluble recombinant trimer
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P2860
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A Prominent Site of Antibody V ...... and Its Camouflaging Glycans.
@en
type
label
A Prominent Site of Antibody V ...... and Its Camouflaging Glycans.
@en
prefLabel
A Prominent Site of Antibody V ...... and Its Camouflaging Glycans.
@en
P2093
P2860
P1433
P1476
A Prominent Site of Antibody V ...... g and Its Camouflaging Glycans
@en
P2093
Alejandra Ramos
Andrew B Ward
Bryan Briney
Chi-Huey Wong
Chi-Hui Liang
Chung-Yi Wu
Dennis R Burton
Ian A Wilson
Jessica Hsueh
P2860
P356
10.1016/J.IMMUNI.2016.06.026
P407
P577
2016-07-01T00:00:00Z