Allelic exchange in Francisella tularensis using PCR products.
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Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for VirulenceThe Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence.In vivo Himar1-based transposon mutagenesis of Francisella tularensis.A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogateFrancisella tularensis T-cell antigen identification using humanized HLA-DR4 transgenic mice.Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicidaEnhancement of vaccine efficacy by expression of a TLR5 ligand in the defined live attenuated Francisella tularensis subsp. novicida strain U112ΔiglB::fljB.Characterization of the O-antigen polymerase (Wzy) of Francisella tularensis.Lipidation of the FPI protein IglE contributes to Francisella tularensis ssp. novicida intramacrophage replication and virulence.3-Deoxy-D-manno-octulosonic acid (Kdo) hydrolase identified in Francisella tularensis, Helicobacter pylori, and Legionella pneumophila.Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS).Cellular and humoral immunity are synergistic in protection against types A and B Francisella tularensis.Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis.Identification of Francisella tularensis genes affected by iron limitation.Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulenceTryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense.Intra-Vacuolar Proliferation of F. Novicida within H. VermiformisDiscovery of a role for Hsp82 in Histoplasma virulence through a quantitative screen for macrophage lethality.Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensis.Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts.Francisella tularensis replicates within alveolar type II epithelial cells in vitro and in vivo following inhalation.Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes.Tularaemia: bioterrorism defence renews interest in Francisella tularensis.Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophagesCyclic di-GMP stimulates biofilm formation and inhibits virulence of Francisella novicida.Characterization and application of a glucose-repressible promoter in Francisella tularensisKdo hydrolase is required for Francisella tularensis virulence and evasion of TLR2-mediated innate immunity.A conserved and immunodominant lipoprotein of Francisella tularensis is proinflammatory but not essential for virulenceThe early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression.Modulation of virulence factors in Francisella tularensis determines human macrophage responses.Contribution of citrulline ureidase to Francisella tularensis strain Schu S4 pathogenesisCharacterization of rationally attenuated Francisella tularensis vaccine strains that harbor deletions in the guaA and guaB genes.Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages.MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival.Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development.Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape.A Francisella tularensis pathogenicity island required for intramacrophage growth.Use of transposon-transposase complexes to create stable insertion mutant strains of Francisella tularensis LVS.Genetic manipulation of francisella tularensis.
P2860
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P2860
Allelic exchange in Francisella tularensis using PCR products.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Allelic exchange in Francisella tularensis using PCR products.
@en
type
label
Allelic exchange in Francisella tularensis using PCR products.
@en
prefLabel
Allelic exchange in Francisella tularensis using PCR products.
@en
P2093
P1476
Allelic exchange in Francisella tularensis using PCR products.
@en
P2093
Bernard P Arulanandam
Crystal M Lauriano
Francis E Nano
Jeffrey R Barker
Karl E Klose
P304
P356
10.1016/S0378-1097(03)00820-6
P577
2003-12-01T00:00:00Z