The effects of post-translational processing on dystroglycan synthesis and trafficking.
about
A comparative study of alpha-dystroglycan glycosylation in dystroglycanopathies suggests that the hypoglycosylation of alpha-dystroglycan does not consistently correlate with clinical severityTargeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethalityMutagenesis at the alpha-beta interface impairs the cleavage of the dystroglycan precursor.High throughput screening for compounds that alter muscle cell glycosylation identifies new role for N-glycans in regulating sarcolemmal protein abundance and laminin bindingProcessing and assembly of the dystrophin glycoprotein complex.Inhibition of proteasome activity promotes the correct localization of disease-causing alpha-sarcoglycan mutants in HEK-293 cells constitutively expressing beta-, gamma-, and delta-sarcoglycan.The rapid decrease in astrocyte-associated dystroglycan expression by focal cerebral ischemia is protease-dependent.The neurobiology of the dystrophin-associated glycoprotein complex.Finding the sweet spot: assembly and glycosylation of the dystrophin-associated glycoprotein complex.Dystroglycan is associated to the disulfide isomerase ERp57.Differential expression profiles between α-dystroglycan and integrin β1 in ameloblastoma: two possible perlecan signalling pathways for cellular growth and differentiation.Filamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression.An extracellular pathway for dystroglycan function in acetylcholine receptor aggregation and laminin deposition in skeletal myotubes.A dystroglycan mutation (p.Cys667Phe) associated to muscle-eye-brain disease with multicystic leucodystrophy results in ER-retention of the mutant protein.Immunodetection of partially glycosylated isoforms of alpha-dystroglycan by a new monoclonal antibody against its beta-dystroglycan-binding epitope.Cys669-Cys713 disulfide bridge formation is a key to dystroglycan cleavage and subunit association.
P2860
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P2860
The effects of post-translational processing on dystroglycan synthesis and trafficking.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The effects of post-translational processing on dystroglycan synthesis and trafficking.
@en
type
label
The effects of post-translational processing on dystroglycan synthesis and trafficking.
@en
prefLabel
The effects of post-translational processing on dystroglycan synthesis and trafficking.
@en
P2093
P2860
P1433
P1476
The effects of post-translational processing on dystroglycan synthesis and trafficking.
@en
P2093
Chris T Esapa
Derek J Blake
Graham R B Bentham
Jörn E Schröder
Stephan Kröger
P2860
P304
P356
10.1016/S0014-5793(03)01230-4
P407
P577
2003-12-01T00:00:00Z