Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase.
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Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPaseThe atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamicsRhoGDI: multiple functions in the regulation of Rho family GTPase activitiesThe 'invisible hand': regulation of RHO GTPases by RHOGDIsRho GTPase regulation by miRNAs and covalent modificationsVav family exchange factors: an integrated regulatory and functional viewInnate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogenSrc and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B.Tyrosine phosphorylation of Rac1: a role in regulation of cell spreadingRhoGDI3 and RhoG: Vesicular trafficking and interactions with the Sec3 Exocyst subunit.Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPasesRegulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src.Polarity proteins and cell-cell interactions in the testis.Differential phosphorylation of RhoGDI mediates the distinct cycling of Cdc42 and Rac1 to regulate second-phase insulin secretion.YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cellsTyrosine phosphorylation of Dbl regulates GTPase signalingPLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cellsSrc promotes GTPase activity of Ras via tyrosine 32 phosphorylation.Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization.Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation.RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.A conserved role of IQGAP1 in regulating TOR complex 1Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells.Cdc42: an effector and regulator of ErbB1 as a strategic target in breast cancer therapy.Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migrationIntegrin regulation of caveolin function.Deregulation of Rho GTPases in cancerImpact of heat-shock protein 90 on cancer metastasisEmerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septinsWnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors.Phosphorylation of Rac1 T108 by extracellular signal-regulated kinase in response to epidermal growth factor: a novel mechanism to regulate Rac1 functionVAV2 regulates epidermal growth factor receptor endocytosis and degradation.Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation.Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in pancreatic beta-cells.Carbachol-mediated endocytosis of NHE3 involves a clathrin-independent mechanism requiring lipid rafts and Cdc42.Reconstruction of the temporal signaling network in Salmonella-infected human cellsCdc42 induces EGF receptor protein accumulation and promotes EGF receptor nuclear transport and cellular transformation.Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.
P2860
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P2860
Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Epidermal growth factor-depend ...... ed by the Src tyrosine kinase.
@en
type
label
Epidermal growth factor-depend ...... ed by the Src tyrosine kinase.
@en
prefLabel
Epidermal growth factor-depend ...... ed by the Src tyrosine kinase.
@en
P2093
P356
P1476
Epidermal growth factor-depend ...... ed by the Src tyrosine kinase.
@en
P2093
Jiabin Wang
Richard A Cerione
Wen Jin Wu
P304
49293-49300
P356
10.1074/JBC.M307021200
P407
P577
2003-09-23T00:00:00Z