BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.
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Cullin-RING ubiquitin ligases: global regulation and activation cyclesUpdate on the Kelch-like (KLHL) gene familyTumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extensionUbiquitin-dependent regulation of COPII coat size and functionThe Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responsesAn FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complexMammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repairHuman SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleasesThe Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cellsThe collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesisUbiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutationTranslational homeostasis via the mRNA cap-binding protein, eIF4EProtein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligaseVHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligasesKCTD5, a putative substrate adaptor for cullin3 ubiquitin ligasesThe Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesisSPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancerTranscriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesisStable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligaseBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseKeap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.Systematic analysis and nomenclature of mammalian F-box proteinsArabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein DegradationOxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activityBTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligaseSCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiaeCyclin D1 down-regulation is essential for DBC2's tumor suppressor functionThe Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimerSequence and structural analysis of BTB domain proteinsPCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexesNRF2, a Key Regulator of Antioxidants with Two Faces towards CancerE3 ubiquitin ligases promote progression of differentiation during C. elegans embryogenesisStructures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesMultimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin LigasesStructural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulationKCTD10 is involved in the cardiovascular system and Notch signaling during early embryonic developmentRedox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degronThe SCF ubiquitin ligase: insights into a molecular machine
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BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
BTB proteins are substrate-spe ...... uitin ligase containing CUL-3.
@en
type
label
BTB proteins are substrate-spe ...... uitin ligase containing CUL-3.
@en
prefLabel
BTB proteins are substrate-spe ...... uitin ligase containing CUL-3.
@en
P2093
P2860
P356
P1433
P1476
BTB proteins are substrate-spe ...... uitin ligase containing CUL-3.
@en
P2093
J Wade Harper
Jerome Reboul
Marc Vidal
Stephen J Elledge
Tae-Ho Shin
P2860
P2888
P304
P356
10.1038/NATURE01985
P407
P577
2003-09-03T00:00:00Z
P6179
1011468688