Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
about
Dysregulated axonal RNA translation in amyotrophic lateral sclerosisMotor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.Therapeutic opportunities and challenges of induced pluripotent stem cells-derived motor neurons for treatment of amyotrophic lateral sclerosis and motor neuron disease.Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors.FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons.Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteinsMelanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response.C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.[Neuronal cells derived from induced pluripotent stem cells to model motoneuron diseases].
P2860
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P2860
Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Stepwise acquirement of hallma ...... ation type and neuronal aging.
@en
type
label
Stepwise acquirement of hallma ...... ation type and neuronal aging.
@en
prefLabel
Stepwise acquirement of hallma ...... ation type and neuronal aging.
@en
P2093
P1476
Stepwise acquirement of hallma ...... ation type and neuronal aging.
@en
P2093
Alexander Storch
Andreas Hermann
Julia Japtok
Marcel Naumann
Maria Demestre
Moritz Klingenstein
Peter Reinhardt
Stefan Liebau
Stefan Putz
Tobias M Boeckers
P304
P356
10.1016/J.NBD.2015.07.017
P577
2015-08-04T00:00:00Z