Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding.
about
ADAM17 (TACE) regulates TGFβ signaling through the cleavage of vasorinADAM-17: the enzyme that does it all.Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte traffickingA mechanism of male germ cell apoptosis induced by bisphenol-A and nonylphenol involving ADAM17 and p38 MAPK activation.Proteomic identification of desmoglein 2 and activated leukocyte cell adhesion molecule as substrates of ADAM17 and ADAM10 by difference gel electrophoresis.Ectodomain shedding of preadipocyte factor 1 (Pref-1) by tumor necrosis factor alpha converting enzyme (TACE) and inhibition of adipocyte differentiationRole of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence.Molecular and cellular mechanisms of ectodomain sheddingMolecular mechanisms of soluble cytokine receptor generation.Application of structural dynamic approaches provide novel insights into the enzymatic mechanism of the tumor necrosis factor-alpha-converting enzymeMetalloproteinase- and gamma-secretase-mediated cleavage of protein-tyrosine phosphatase receptor type ZMitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts.Vitamin D inhibition of TACE and prevention of renal osteodystrophy and cardiovascular mortalityThe Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer's Disease.Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates.Post-transcriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors.Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family membersA role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44Amino-terminal TACE prodomain attenuates TNFR2 cleavage independently of the cysteine switch.Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-alpha converting enzyme (TACE).Expression of the anti-amyloidogenic secretase ADAM10 is suppressed by its 5'-untranslated region.Regulated cell surface pro-EGF ectodomain shedding is a zinc metalloprotease-dependent process.Mouse ADAM33: two splice variants differ in protein maturation and localization.The shedding of betaglycan is regulated by pervanadate and mediated by membrane type matrix metalloprotease-1.Regulated shedding of PAR1 N-terminal exodomain from endothelial cells.Selective and specific regulation of ectodomain shedding of angiotensin-converting enzyme 2 by tumor necrosis factor alpha-converting enzyme.Pancreatic cancer heterogeneity and response to Mek inhibition.Developing a microfluidic-based system to quantify cell capture efficiency.
P2860
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P2860
Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Impaired trafficking and activ ...... n protein ectodomain shedding.
@en
type
label
Impaired trafficking and activ ...... n protein ectodomain shedding.
@en
prefLabel
Impaired trafficking and activ ...... n protein ectodomain shedding.
@en
P2093
P2860
P356
P1476
Impaired trafficking and activ ...... in protein ectodomain shedding
@en
P2093
Aldo Borroto
Anna Merlos-Suarez
Atanasio Pandiella
Carl P Blobel
Joaquin Arribas
Josep Baselga
Soraya Ruiz-Paz
Teresa Villanueva de la Torre
P2860
P304
25933-25939
P356
10.1074/JBC.M301673200
P407
P577
2003-04-24T00:00:00Z