Protein tyrosine kinase activities of the epidermal growth factor receptor and ErbB proteins: correlation of oncogenic activation with altered kinetics.
about
Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.Constitutive activation of the RON gene promotes invasive growth but not transformation.Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain.Tyrosine kinase activity may be necessary but is not sufficient for c-erbB1-mediated tissue-specific tumorigenicityIn-frame deletion in the EGF receptor alters kinase inhibition by gefitinib.
P2860
Protein tyrosine kinase activities of the epidermal growth factor receptor and ErbB proteins: correlation of oncogenic activation with altered kinetics.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Protein tyrosine kinase activi ...... ivation with altered kinetics.
@en
type
label
Protein tyrosine kinase activi ...... ivation with altered kinetics.
@en
prefLabel
Protein tyrosine kinase activi ...... ivation with altered kinetics.
@en
P2093
P2860
P356
P1476
Protein tyrosine kinase activi ...... ivation with altered kinetics.
@en
P2093
P2860
P304
P356
10.1128/MCB.12.5.2010
P407
P577
1992-05-01T00:00:00Z