A large scale genetic analysis of c-Myc-regulated gene expression patterns. - Wikidata - awgldk - TriplyDB

A large scale genetic analysis of c-Myc-regulated gene expression patterns.

A large scale genetic analysis of c-Myc-regulated gene expression patterns.

http://www.wikidata.org/entity/Q40677486

about

mrtl-A translation/localization regulatory protein encoded within the human c-myc locus and distributed throughout the endoplasmic and nucleoplasmic reticular network Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors Genomic targets of the human c-Myc protein The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth hTERT protein expression is independent of clinicopathological parameters and c-Myc protein expression in human breast cancer Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma Cancer metabolism: key players in metabolic reprogramming Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor Regulation of energy metabolism pathways by estrogens and estrogenic chemicals and potential implications in obesity associated with increased exposure to endocrine disruptors Mnt transcriptional repressor is functionally regulated during cell cycle progression The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression Proteomes and signalling pathways of antler stem cells Reverse engineering of regulatory networks in human B cells PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function.Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation.Reconstructing networks of pathways via significance analysis of their intersections.Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis Global regulation of nucleotide biosynthetic genes by c-Myc A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response Targeting MYC Dependence by Metabolic Inhibitors in Cancer MYC and the control of DNA replication.Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes.Targeting c-Myc-activated genes with a correlation method: detection of global changes in large gene expression network dynamics.In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation.hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation.The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy.c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.The Max b-HLH-LZ can transduce into cells and inhibit c-Myc transcriptional activities.Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts.MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer.The biology of human lymphoid malignancies revealed by gene expression profiling.Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation

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P2860

A large scale genetic analysis of c-Myc-regulated gene expression patterns.

http://www.wikidata.org/entity/Q40677486

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

A large scale genetic analysis of c-Myc-regulated gene expression patterns.

@en

type

label

A large scale genetic analysis of c-Myc-regulated gene expression patterns.

@en

prefLabel

A large scale genetic analysis of c-Myc-regulated gene expression patterns.

@en

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Journal of Biological Chemistry

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A large scale genetic analysis of c-Myc-regulated gene expression patterns.

@en

P2093

Ann F Cheung

http://www.w3.org/2001/XMLSchema#string

Brenda C O'Connell

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Carl P Simkevich

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John M Sedivy

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Wanny Tam

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Xiaojia Ren

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P2860

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.

The Myc/Max/Mad network and the transcriptional control of cell behavior

Repression of p15INK4b expression by Myc through association with Miz-1

The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression

A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism

Production of high-titer helper-free retroviruses by transient transfection

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis.

Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis

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12563-12573

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scholarly article

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10.1074/JBC.M210462200

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14

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278

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12529326

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