Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.
about
Novel targeted therapies for Bcr-Abl positive acute leukemias: beyond STI571.The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene productsMutations affecting the MA portion of the v-Abl protein reveal a conserved role of Gag in Abelson murine leukemia virus (MLV) and Moloney MLVMutational analysis of the regulatory function of the c-Abl Src homology 3 domain.The murine AIDS virus Gag precursor protein binds to the SH3 domain of c-AblHormone-conditional transformation by fusion proteins of c-Abl and its transforming variantsInterplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein.The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-AblGag influences transformation by Abelson murine leukemia virus and suppresses nuclear localization of the v-Abl proteinThe COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity.Characterization of the myristylated polypeptide encoded by the UL1 gene that is conserved in the genome of defective interfering particles of equine herpesvirus 1Myristoylation of the G alpha i2 polypeptide, a G protein alpha subunit, is required for its signaling and transformation functions.v-Abl activates c-myc transcription through the E2F site.An activating mutation in the ATP binding site of the ABL kinase domain.The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferationSubcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation.An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemiasP210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members.Membrane association of the myristoylated alanine-rich C kinase substrate (MARCKS) protein. Mutational analysis provides evidence for complex interactions.Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line.
P2860
Q27824789-F721FB7B-9FAD-482F-B71D-55337FF876F8Q28508496-583EEA88-C465-47D9-B0BC-729EB0B9EDE4Q28754439-3F9DBF25-8B7F-4057-95D6-BD8ED1B0AB51Q30167708-EA8C028A-B33D-4F0D-B02B-3435B4F376E6Q30176596-448438A3-F5B0-4E31-B51A-36C04AAA790BQ30194953-D9AF5EB9-6CE3-4EA9-B20C-7F4CBC260BBCQ33828334-8C7C9B99-5471-4DFB-848F-FF82EAB44223Q33885920-5730A57E-DD5A-468C-8F83-270C0FCCBE3FQ33967112-612F0ED3-F5C4-45B8-934D-3204CA1DDB8CQ35947927-D02FA936-6F2B-48CD-AF5D-ABA8916CFCDEQ36233735-D7C14CBF-A7EC-4DEA-8412-30253E8B0F9BQ36650139-9F051340-44E0-47EC-8723-8F70ADB2235BQ37249953-A7392BD8-4F4B-46B9-8C6E-6BEC305AA72CQ38288618-0F06D14C-A4C5-44E8-8FCE-7CA1547B0337Q38354181-334AB9D0-4FA9-4973-8880-980C3C04B4ACQ40015747-4A6C5E5E-A27E-4AFC-83BA-523DFC2C5B19Q40305409-27DA33E4-C2FC-4E4F-A8FB-74DD3039B27AQ40872589-7894EB75-F2A7-4FA3-A69F-BB0A3355E572Q41145752-E1E3BA67-5400-48DE-A983-46AEDC612E69Q41336364-15AE5450-703D-48C2-BED2-78C9C0E6F556Q41576170-E0BCD937-B133-42A4-9A0D-2AC62A63A3F1
P2860
Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.
@en
type
label
Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.
@en
prefLabel
Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.
@en
P2093
P2860
P356
P1476
Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.
@en
P2093
A Bernards
D Baltimore
P K Jackson
R A Van Etten
P2860
P304
P356
10.1128/MCB.12.4.1864
P407
P577
1992-04-01T00:00:00Z