Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors.
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An analysis of enzyme kinetics data for mitochondrial DNA strand termination by nucleoside reverse transcription inhibitorsIn vivo assessment of mitochondrial toxicity of metacavir in Rhesus monkeys after three months of intravenous administration.Tenofovir renal toxicity targets mitochondria of renal proximal tubules.Anticoagulant therapy for nodular regenerative hyperplasia in a HIV-infected patient.Mitochondrial DNA depletion and respiratory chain activity in primary human subcutaneous adipocytes treated with nucleoside analogue reverse transcriptase inhibitorsInhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.Potent anti-R5 human immunodeficiency virus type 1 effects of a CCR5 antagonist, AK602/ONO4128/GW873140, in a novel human peripheral blood mononuclear cell nonobese diabetic-SCID, interleukin-2 receptor gamma-chain-knocked-out AIDS mouse model.Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIVEnhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells.Zidovudine induces downregulation of mitochondrial deoxynucleoside kinases: implications for mitochondrial toxicity of antiviral nucleoside analogs.Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus.Miller Fisher variant of Guillain-Barré syndrome associated with lactic acidosis and stavudine therapy.Initial antiretroviral therapy in chronically-infected HIV-positive adults.Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in ratsImpact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy.Progression of Liver Fibrosis and Modern Combination Antiretroviral Therapy Regimens in HIV-Hepatitis C-Coinfected Persons.Mitochondrial disease in the offspring as a result of antiretroviral therapy.Pyrimidine nucleoside depletion sensitizes to the mitochondrial hepatotoxicity of the reverse transcriptase inhibitor stavudine.Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes.Physical fitness in children infected with the human immunodeficiency virus: associations with highly active antiretroviral therapyBrief Report: Switch to Ritonavir-Boosted Atazanavir Plus Raltegravir in Virologically Suppressed Patients With HIV-1 Infection: A Randomized Pilot Study.Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cellsThe Use of the Medical Dictionary for Regulatory Activities in the Identification of Mitochondrial Dysfunction in HIV-Infected Children.Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion.Potent activity of a nucleoside reverse transcriptase inhibitor, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinaseIncreased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapyEffects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress.Treatment-limiting toxicities associated withnucleoside analogue reverse transcriptase inhibitor therapy: A prospective, observational studyNutrition and the HIV-associated lipodystrophy syndrome.Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors.The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction.In vitro supplementation with deoxynucleoside monophosphates rescues mitochondrial DNA depletion.The Use of Cytochrome C Oxidase Enzyme Activity and Immunohistochemistry in Defining Mitochondrial Injury in Kidney DiseaseChanging utilization of Stavudine (d4T) in HIV-positive people in 2006-2013 in the EuroSIDA study.Mitochondrial and Oxidative Stress Response in HepG2 Cells Following Acute and Prolonged Exposure to Antiretroviral Drugs.Long-term exposure of mice to nucleoside analogues disrupts mitochondrial DNA maintenance in cortical neurons.Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition.Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells.Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy.
P2860
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P2860
Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Increased long-term mitochondr ...... erse-transcriptase inhibitors.
@en
type
label
Increased long-term mitochondr ...... erse-transcriptase inhibitors.
@en
prefLabel
Increased long-term mitochondr ...... erse-transcriptase inhibitors.
@en
P2093
P1433
P1476
Increased long-term mitochondr ...... erse-transcriptase inhibitors.
@en
P2093
Bernhard Setzer
Nils Venhoff
Ulrich A Walker
P304
P356
10.1097/00002030-200211080-00009
P407
P577
2002-11-01T00:00:00Z