Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration.
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Mechanism and effect of thrombospondin-4 polymorphisms on neutrophil functionCrystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptideUrokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory diseaseThe urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingDistinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2Nuclear translocation of urokinase-type plasminogen activatorIdentification of a negatively charged peptide motif within the catalytic domain of progelatinases that mediates binding to leukocyte beta 2 integrins.Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region.In silico docking of urokinase plasminogen activator and integrins.Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblastsNeutrophil apoptosis: selective regulation by different ligands of integrin alphaMbeta2.Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator.Regulation of innate immune response to Candida albicans infections by αMβ2-Pra1p interaction.Molecular and functional interdependence of the urokinase-type plasminogen activator system with integrins.Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulationRegulation of alpha5beta1 integrin conformation and function by urokinase receptor binding.Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticlesUrokinase-type plasminogen activator modulates airway eosinophil adhesion in asthma.Urokinase-mediated recruitment of myeloid-derived suppressor cells and their suppressive mechanisms are blocked by MUC1/sec.An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.Distinct Effects of Integrins αXβ2 and αMβ2 on Leukocyte Subpopulations during Inflammation and Antimicrobial Responses.Plasminogen and its receptors as regulators of cardiovascular inflammatory responses.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.Mechanisms of antitumor and immune-enhancing activities of MUC1/sec, a secreted form of mucin-1.Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression.A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor.A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth.Regulation of urokinase receptor proteolytic function by the tetraspanin CD82.Species-specific urokinase receptor ligands reduce glioma growth and increase survival primarily by an antiangiogenesis mechanism.Dual role of the leukocyte integrin αMβ2 in angiogenesis.Urokinase-type plasminogen activator inhibits efferocytosis of neutrophils.Effect of urokinase-type plasminogen activator system in gastric cancer with peritoneal metastasis.Differential expression of monocyte/macrophage- selective markers in human idiopathic pulmonary fibrosis.Short fungal fractions of β-1,3 glucans affect platelet activation.Integrin alphaMbeta2 orchestrates and accelerates plasminogen activation and fibrinolysis by neutrophils.Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B.Urokinase-type plasminogen activator receptor induces conformational changes in the integrin alphaMbeta2 headpiece and reorientation of its transmembrane domains.The kringle domain of urokinase-type plasminogen activator potentiates LPS-induced neutrophil activation through interaction with {alpha}V{beta}3 integrins.
P2860
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P2860
Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Convergence of the adhesive an ...... s cell adhesion and migration.
@en
type
label
Convergence of the adhesive an ...... s cell adhesion and migration.
@en
prefLabel
Convergence of the adhesive an ...... s cell adhesion and migration.
@en
P2093
P1433
P1476
Convergence of the adhesive an ...... s cell adhesion and migration.
@en
P2093
Dmitry A Soloviev
Edward F Plow
Elzbieta Pluskota
P304
P356
10.1182/BLOOD-2002-06-1842
P407
P577
2002-09-26T00:00:00Z