Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents.

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Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents.

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

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name

Absorption, distribution, meta ...... -II topoisomerases in rodents.

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Absorption, distribution, meta ...... -II topoisomerases in rodents.

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Absorption, distribution, meta ...... -II topoisomerases in rodents.

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P1476

Absorption, distribution, meta ...... -II topoisomerases in rodents.

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P2093

Camil Joubran

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Gregory S Basarab

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Jian Guo

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Karthick Vishwanathan

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Ricardo A Luzietti

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Scott W Grimm

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P2860

Emerging mechanisms of fluoroquinolone resistance

Structure and mechanism of DNA topoisomerase II

Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.

In vitro and in vivo activities of PD 0305970 and PD 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups

A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system.

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.

Global fluoroquinolone resistance epidemiology and implictions for clinical use.

Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

Bacterial DNA replication enzymes as targets for antibacterial drug discovery.

Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914).

P304

31-49

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scholarly article

P356

10.3109/00498254.2016.1156186

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English

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P478

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P577

2016-04-28T00:00:00Z

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P698

27122100

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