The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
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The HTLV-1 Tax interactomeHighlights on distinctive structural and functional properties of HTLV Tax proteinsThe HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6The bZIP transcription factor ATFx binds human T-cell leukemia virus type 1 (HTLV-1) Tax and represses HTLV-1 long terminal repeat-mediated transcriptionSUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR.Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding proteinRole of accessory proteins of HTLV-1 in viral replication, T cell activation, and cellular gene expression.Newly emerging therapies targeting viral-related lymphomas.The cellular protein daxx interacts with avian sarcoma virus integrase and viral DNA to repress viral transcription.The deacetylase HDAC1 negatively regulates the cardiovascular transcription factor Krüppel-like factor 5 through direct interaction.Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat.Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity.BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisTranscription regulatory complexes bind the human T-cell leukemia virus 5' and 3' long terminal repeats to control gene expression.Direct inhibition of RNAse T2 expression by the HTLV-1 viral protein Tax.Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription.Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code.Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoproteinHistone hyperacetylation during SV40 transcription is regulated by p300 and RNA polymerase II translocation.Cotranscriptional Chromatin Remodeling by Small RNA Species: An HTLV-1 PerspectiveHTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysEffective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25.BCL11B is a general transcriptional repressor of the HIV-1 long terminal repeat in T lymphocytes through recruitment of the NuRD complexOverlapping CRE and E box motifs in the enhancer sequences of the bovine leukemia virus 5' long terminal repeat are critical for basal and acetylation-dependent transcriptional activity of the viral promoter: implications for viral latency.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.Animal models on HTLV-1 and related viruses: what did we learn?Molecular hallmarks of adult T cell leukemia.The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcrp21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded tax.Interaction of HTLV-1 Tax and methyl-CpG-binding domain 2 positively regulates the gene expression from the hypermethylated LTR.SYT, a partner of SYT-SSX oncoprotein in synovial sarcomas, interacts with mSin3A, a component of histone deacetylase complex.Deacetylase inhibitors and the viral transactivator TaxBLV synergistically activate bovine leukemia virus gene expression via a cAMP-responsive element- and cAMP-responsive element-binding protein-dependent mechanism.HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin.Multi-step aberrant CpG island hyper-methylation is associated with the progression of adult T-cell leukemia/lymphomaEpigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemiaTranscription factor binding and histone modifications on the integrated proviral promoter in human T-cell leukemia virus-I-infected T-cells.
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P2860
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
@en
type
label
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
@en
prefLabel
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
@en
P2093
P2860
P356
P1433
P1476
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
@en
P2093
Kunitada Shimotohno
Takeshi Ego
Yasuo Ariumi
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205701
P407
P577
2002-10-01T00:00:00Z
P5875
P6179
1007694632