The cleavage of the urokinase receptor regulates its multiple functions.
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Ly6 family proteins in neutrophil biologySingle amino acid substitutions in the chemotactic sequence of urokinase receptor modulate cell migration and invasionRegulatory systems in bone marrow for hematopoietic stem/progenitor cells mobilization and homing.The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingSoluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling.Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.Plasmin cleaves the juxtamembrane domain and releases truncated species of the urokinase receptor (CD87) from human bronchial epithelial cells.Urokinase receptor (CD87) clustering in detergent-insoluble adhesion patches leads to cell adhesion independently of integrins.Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas.Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion.Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus.The role of vascular actors in two dimensional dialogue of human bone marrow stromal cell and endothelial cell for inducing self-assembled network.Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes.Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence.Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly.Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixturesExpression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healingUrokinase and its receptors in chronic kidney disease.Cyclization of the urokinase receptor-derived ser-arg-ser-arg-tyr Peptide generates a potent inhibitor of trans-endothelial migration of monocytes.Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion.Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity.Lipoprotein receptor-related protein 1 regulates collagen 1 expression, proteolysis, and migration in human pleural mesothelial cells.Urokinase receptor cleavage: a crucial step in fibroblast-to-myofibroblast differentiation.Dissecting mannose 6-phosphate-insulin-like growth factor 2 receptor complexes that control activation and uptake of plasminogen in cells.Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.Tumor-associated soluble uPAR-directed endothelial cell motility and tumor angiogenesis.Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2Urokinase-type plasminogen activator modulates airway eosinophil adhesion in asthma.Fluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor.Urokinase type plasminogen activator receptor (uPAR) as a new therapeutic target in cancer.The urokinase receptor-derived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells.The plasminogen system in regulating stem cell mobilization.The urokinase receptor takes control of cell migration by recruiting integrins and FPR1 on the cell surfaceTumourigenicity and radiation resistance of mesenchymal stem cells.The cross-talk between the urokinase receptor and fMLP receptors regulates the activity of the CXCR4 chemokine receptor.Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases.An urokinase receptor antagonist that inhibits cell migration by blocking the formyl peptide receptor.The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style.A cleavage-resistant urokinase plasminogen activator receptor exhibits dysregulated cell-surface clearance.Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells.
P2860
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P2860
The cleavage of the urokinase receptor regulates its multiple functions.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The cleavage of the urokinase receptor regulates its multiple functions.
@en
type
label
The cleavage of the urokinase receptor regulates its multiple functions.
@en
prefLabel
The cleavage of the urokinase receptor regulates its multiple functions.
@en
P2093
P2860
P356
P1476
The cleavage of the urokinase receptor regulates its multiple functions.
@en
P2093
Guido Rossi
Maria Vincenza Carriero
Nunzia Montuori
Salvatore Salzano
P2860
P304
46932-46939
P356
10.1074/JBC.M207494200
P407
P577
2002-09-23T00:00:00Z