Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion.
about
DNA demethylation and invasive cancer: implications for therapeuticsBreast cancer epigenetics: from DNA methylation to microRNAsIdentification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profilingGenome-wide analysis in human colorectal cancer cells reveals ischemia-mediated expression of motility genes via DNA hypomethylationInhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs.Transcriptional regulation of the human growth hormone receptor (hGHR) gene V2 promoter by transcriptional activators and repressor.The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity.Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genesDNA methylation regulates expression of VEGF-C, and S-adenosylmethionine is effective for VEGF-C methylation and for inhibiting cancer growth.Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancerMethylation target array for rapid analysis of CpG island hypermethylation in multiple tissue genomesInterleukin-1 alpha promotes tumor growth and cachexia in MCF-7 xenograft model of breast cancer.Upregulated expression of Ezrin and invasive phenotype in malignantly transformed esophageal epithelial cellsInhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator.Therapeutic implications of DNA methylation.Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.The role of epigenetic alterations in pancreatic cancer.A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness.Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation.Suppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells.Epigenetic up-regulation of leukemia inhibitory factor (LIF) gene during the progression to breast cancer.Modulators of the urokinase-type plasminogen activation system for cancer.Epigenetic alterations involved in cancer stem cell reprogramming.The methylation landscape of tumour metastasis.Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis.DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation.Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231.The pharmacoepigenetics of drug metabolism and transport in breast cancer: review of the literature and in silico analysis.Synergistic anti-breast cancer effect of a combined treatment with the methyl donor S-adenosyl methionine and the DNA methylation inhibitor 5-aza-2'-deoxycytidine.A tumor suppressor role for srGAP3 in mammary epithelial cells.Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine.The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines.S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells.A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties.Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications.Epigenetic Mechanisms in Cancer Formation and ProgressionDecreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers
P2860
Q27011914-E302E5F0-56C7-49A7-B390-E5A829332095Q27694164-9E9FE163-E5CF-413B-A132-44B699C44D2BQ28238147-4D1512B9-F48D-477B-A16F-2684BD2A6965Q28391482-21769F35-07D9-43C8-8D17-0FB8407A111BQ30437958-452E5AB6-5CB1-416E-A0BE-FA6BA6B8F357Q33670512-DB70B7F0-71D6-4002-8307-66E19321165DQ34204135-7C9AD1AD-570F-45C1-AB7B-5A0FBC292CD0Q34310075-FFF576E8-E3B7-407A-97DB-EC770D676FA8Q34574257-1E123A7B-CFD6-45A9-9497-0437044F486EQ35000289-17B4CA44-09EE-4865-B97A-E2A5DA8B2BA9Q35121612-EB56C768-F484-47B5-93FA-38112D0B4FE6Q35791618-F7C06EB8-BC5F-4E2A-AD9F-558416FA31FBQ35843346-B2A671EA-1B4C-45EF-8D78-6F428303753EQ36179753-98F25C46-5AC5-48D6-82A1-4CBB67CEE708Q36302249-82E4549F-B235-4AC8-A8B7-E21CF07222F2Q36429409-2EB7137E-1515-4689-9368-4118F29C968BQ36485293-493B1692-CF3C-4CE4-81B6-2F15F6F8EF50Q36542828-60DB869F-1879-4F82-8D42-2CFB02BAFB7DQ36545127-E4112CBE-9418-4F5D-A18A-26B4E65FC21AQ36579350-65D82877-9ABE-40EB-AE4F-5769C4F65BA6Q36740700-C12FBC75-DAA7-4A50-9079-1D0FAA7B6204Q37599413-399BF396-7723-4434-A058-CF829634F8C6Q37733590-E4B377AE-9F28-4E1B-9F70-D47DA6E596D6Q38058972-E5700C8E-A865-4CFC-B94B-E21A07ACEC75Q38063931-1A72331B-B39D-4BBE-9D09-9C84608A10DBQ38341003-9C33DC20-B421-4311-BCC1-A9F332E5437BQ38342368-E8311493-8175-4AC7-B7DE-822C8D50A4ECQ38914216-17EE0DD2-2A69-4140-8700-0F0C1528CE85Q38937221-C899380E-05BB-4605-B882-686C8719D487Q39103683-30685742-13A3-4F29-BFC2-ACE28FD90B89Q39251879-0CA53850-451A-4BDC-A95E-115BAA736B17Q39480395-86D4D7A7-34B3-46ED-8E35-083E10621447Q40040225-04F199F8-3CFE-4350-8616-A49E77791371Q47555147-A239CA96-9722-4C94-B2A9-D491816FABE4Q51089323-8E27FE14-DE94-4004-AE21-ED7318AD4607Q54960825-E777F2D2-8984-416C-98E0-A36115703F9DQ57570317-413A9E1E-50FB-4D43-AF1E-25242483E734Q58761810-4BB9BA12-0FAA-448C-88F9-E31A77FC836C
P2860
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Regulation of DNA methylation ...... production and tumor invasion.
@en
type
label
Regulation of DNA methylation ...... production and tumor invasion.
@en
prefLabel
Regulation of DNA methylation ...... production and tumor invasion.
@en
P2093
P356
P1476
Regulation of DNA methylation ...... production and tumor invasion.
@en
P2093
Andrew Slack
Julienne Gladu
Moshe Szyf
Pouya Pakneshan
Shafaat A Rabbani
Yongjing Guo
P304
41571-41579
P356
10.1074/JBC.M201864200
P407
P577
2002-08-26T00:00:00Z