Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment.
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In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitisSevere diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice.Placental and fetal disposition of mercuric ions in rats exposed to methylmercury: role of Mrp2.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Use of in vitro transporter assays to understand hepatic and renal disposition of new drug candidates.A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk.Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis.Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2).Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver.Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes.New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.Effect of Liver Disease on Hepatic Transporter Expression and Function.Relationship between drug/metabolite exposure and impairment of excretory transport function.Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics II: Studies with isolated perfused rat liver.Bromobenzene-induced hepatotoxicity at the transcriptome level.Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics. III: mechanisms for sinusoidal efflux of 4-methylumbelliferone sulfate.Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride.Coordinated expression of multidrug resistance-associated proteins (Mrps) in mouse liver during toxicant-induced injury.
P2860
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P2860
Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mechanisms of impaired biliary ...... or phenobarbital pretreatment.
@en
type
label
Mechanisms of impaired biliary ...... or phenobarbital pretreatment.
@en
prefLabel
Mechanisms of impaired biliary ...... or phenobarbital pretreatment.
@en
P2093
P356
P1476
Mechanisms of impaired biliary ...... or phenobarbital pretreatment.
@en
P2093
Gary M Pollack
Hiroshi Suzuki
Kim L R Brouwer
Peter J Meier
Yuichi Sugiyama
P304
P356
10.1124/DMD.30.9.962
P577
2002-09-01T00:00:00Z