WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.
about
Matricellular proteins: a sticky affair with cancersWISP3, the gene responsible for the human skeletal disease progressive pseudorheumatoid dysplasia, is not essential for skeletal function in miceOn how CCN6 suppresses breast cancer growth and invasionNormal growth and development in mice over-expressing the CCN family member WISP3WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancerUpdate on inflammatory breast cancerA structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesisInflammatory breast cancer: relationship between growth factor signaling and motility in aggressive cancersInhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.Inflammatory breast cancer: New factors contribute to disease etiology: A reviewTaking aim at the extracellular matrix: CCN proteins as emerging therapeutic targetsIn vitro propagation and transcriptional profiling of human mammary stem/progenitor cellsEpigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cellsMMTV-cre;Ccn6 knockout mice develop tumors recapitulating human metaplastic breast carcinomas.High-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes.Alternate estrogen receptors promote invasion of inflammatory breast cancer cells via non-genomic signalingSilencing of WISP3 suppresses gastric cancer cell proliferation and metastasis and inhibits Wnt/β-catenin signalingA molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers.Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.WISP3 (CCN6) is a secreted tumor-suppressor protein that modulates IGF signaling in inflammatory breast cancerCCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancerA Wisp3 Cre-knockin allele produces efficient recombination in spermatocytes during early prophase of meiosis I.Apoptosis signal-regulating kinase 1 is involved in WISP-1-promoted cell motility in human oral squamous cell carcinoma cellsNew insight into CCN3 interactions--nuclear CCN3 : fact or fantasy?Nephroblastoma overexpressed gene (NOV) enhances RCC cell motility through upregulation of ICAM-1 and COX-2 expression via Akt pathway.The CCN3 (NOV) cell growth regulator: a new tool for molecular medicine.Stem cells in normal breast development and breast cancer.WISP-1 a novel angiogenic regulator of the CCN family promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression.Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina.The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signalingCCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer.CCN6 knockdown disrupts acinar organization of breast cells in three-dimensional cultures through up-regulation of type III TGF-β receptor.WISP3 is highly expressed in a subset of colorectal carcinomas with a better prognosis.Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localizationDistinct molecular phenotype of inflammatory breast cancer compared to non-inflammatory breast cancer using Affymetrix-based genome-wide gene-expression analysis.CCN6 (WISP3) as a new regulator of the epithelial phenotype in breast cancer.WISP-1 promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells.Expression of CCN family of genes in human skin in vivo and alterations by solar-simulated ultraviolet irradiation.Prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (IBC): analysis of 2,014 IBC patient cases from the California Cancer Registry
P2860
Q21296660-9DFA57FA-4B02-4085-BCFE-0A9B7347BD5EQ24558691-671FCB30-EFC1-47EF-94B0-52BB02CB91C8Q24598488-E2EEA978-44ED-45C4-9FEC-5E86EFE7C980Q24656664-E2A7B5BC-8ED0-4FAE-BBED-42A6DCF9AD86Q24794280-A330B48F-F43C-4C10-863D-AD5BFBCD4978Q24797853-58689329-EF6A-4E16-BBAA-2A2628A5ED9DQ24799083-8CCCDCC4-BF3E-4997-BB95-E74ABBC8774DQ24803667-0C5B9346-880E-4877-8DC8-0CBC1AAA3CC3Q25257817-CA1416B2-0FF7-4361-B57C-3F05D3D4F5F3Q27027856-54C0D300-69ED-4563-BDB3-FCFB6F06781CQ28254386-D72F9F91-8D78-4B91-9CDC-24237395B46AQ29616498-51D280D6-7506-450E-A301-C6028EB4746AQ31138996-06C09B2D-0A98-4057-AAFD-BFE579B16662Q33585917-051DB5B5-26FE-4E42-837D-84DCB3EAA17BQ33826097-DA05E321-8716-4F05-9DB8-A72AE67FC159Q34147662-1EC2FA93-5484-49F1-ACE0-CBAE1F873454Q34501883-6C3ACAA8-F0FA-4A3F-B86A-F204B3764233Q34575966-30FC5D5A-1003-464A-9CF7-10BF1B4680E1Q34698214-DA4668CF-2331-4839-8BD6-123E6C05FDA7Q34770011-DF4D5C23-D7D1-4720-A82A-9054A248665FQ34897573-0C6A9246-0541-4975-A496-C61846B12DA7Q34990540-F5810062-6D74-4DD1-A7BB-17E6A8E4D038Q35035922-81242139-BF9B-431E-95A2-61626169DD67Q35065958-DE670F51-D7FE-4BF3-9B61-06860EE72BF2Q35405995-9A96C849-4534-4B75-A4A2-6054D9D3B0AAQ35543893-161D6D36-C226-476C-8EE9-D5BFF14B6B80Q35548236-A93AD5CF-261A-41C5-92C8-4669870E9AF7Q35551984-816B60F0-887F-420C-8970-DE4DB3A28ECDQ35880995-D6C7FD7C-DFBB-464F-B263-7F6CE6FD5964Q35970905-3499D2F7-38C7-4430-A9A8-924BEA2A29CAQ36422871-4438F728-AD80-422B-AE13-5F02F9062CA1Q36446431-D6952A88-BAAE-4708-A778-B02E8A0869F9Q36473625-445701C3-B72B-4C33-914F-C096DAC05844Q36512260-7D5F0897-1F50-4934-BEE8-19AE07191D7FQ36578825-8E47B389-11C0-4FC4-AAD3-D8559753A24AQ36611440-716C6340-49D4-427D-B534-4A62868E211EQ36857787-3DD55F72-A90C-4F9A-ABF0-2991D4411319Q36962844-36FA1819-7DA0-450F-B8FC-4BBE88372E6FQ37203093-98052546-DF02-4A2D-9D05-3F972E6E6477Q37205563-250C768A-6C7A-4C5F-8393-DD3431303B2A
P2860
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.
@en
type
label
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.
@en
prefLabel
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.
@en
P2093
P2860
P921
P356
P1433
P1476
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.
@en
P2093
Celina G Kleer
Kenneth L van Golen
Quintin Pan
Sofia D Merajver
Yanhong Zhang
Zhi-Fen Wu
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205462
P407
P577
2002-05-01T00:00:00Z
P5875
P6179
1030253321