WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

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Pathogenesis, diagnosis and therapeutic strategies in WHIM syndrome immunodeficiency.Multisystem multitasking by CXCL12 and its receptors CXCR4 and ACKR3.

P2860

Q48624133-E73F0D48-5D19-4489-9181-AE85EA4BEE6C Q49343068-195989EE-BD39-4CF3-B96E-A818372E529A

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WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

Item

http://www.wikidata.org/entity/Q40722797

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

WHIM Syndrome Caused by Walden ...... iated Mutation CXCR4 (L329fs).

@en

type

Item

label

WHIM Syndrome Caused by Walden ...... iated Mutation CXCR4 (L329fs).

@en

prefLabel

WHIM Syndrome Caused by Walden ...... iated Mutation CXCR4 (L329fs).

@en

P1476

WHIM Syndrome Caused by Walden ...... iated Mutation CXCR4 (L329fs).

@en

P2093

Catherina Pan

http://www.w3.org/2001/XMLSchema#string

Daniel Velez

http://www.w3.org/2001/XMLSchema#string

David H McDermott

http://www.w3.org/2001/XMLSchema#string

Donald T Ellenburg

http://www.w3.org/2001/XMLSchema#string

Harry L Malech

http://www.w3.org/2001/XMLSchema#string

Jean Ulrick

http://www.w3.org/2001/XMLSchema#string

Jiliang Gao

http://www.w3.org/2001/XMLSchema#string

John S Corns

http://www.w3.org/2001/XMLSchema#string

Lizbeeth Lopez

http://www.w3.org/2001/XMLSchema#string

Patricia Littel

http://www.w3.org/2001/XMLSchema#string

P2860

AMD3100 is a potent antagonist at CXCR4(R334X) , a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome

The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis

Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome

Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease.

The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome.

A new familial immunodeficiency disorder characterized by severe neutropenia, a defective marrow release mechanism, and hypogammaglobulinemia.

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor

WHIM syndrome: a genetic disorder of leukocyte trafficking.

Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4

CXCR4 mutations in WHIM syndrome: a misguided immune system?

P2888

s10875-016-0276-3

P304

397-405

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scholarly article

P356

10.1007/S10875-016-0276-3

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Sandra Anaya-O'Brien

P577

2016-04-08T00:00:00Z

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P6179

1041293836

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P698

27059040

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WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

about

P2860

P2860

WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

description

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type

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P50

P577

P6179

P698

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P50

P577

P6179

P698