CXCR4 mutations in WHIM syndrome: a misguided immune system?
about
AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signalingWHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptorDOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memoryGenetic variation in CXCL12 and risk of cervical carcinoma: a population-based case-control studyCXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathwaysFamilial occurrence of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndromeDysplasia of Granulocytes in a Patient with HPV Disease, Recurrent Infections, and B Lymphopenia: A Novel Variant of WHIM Syndrome?An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrowGain-of-function CCR4 mutations in adult T cell leukemia/lymphomaConditional inactivation of the CXCR4 receptor in osteoprecursors reduces postnatal bone formation due to impaired osteoblast development.Personalized biochemistry and biophysics.NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation.WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4.Expanded numbers of circulating myeloid dendritic cells in patent human filarial infection reflect lower CCR1 expression.Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targetsWarts and all: human papillomavirus in primary immunodeficiencies.Description and outcome of a cohort of 8 patients with WHIM syndrome from the French Severe Chronic Neutropenia RegistryImmunity to microbes: lessons from primary immunodeficiencies.Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells.Leukocyte trafficking in primary immunodeficiencies.Genetics on a WHIM.Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review.WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).Pathogenesis, diagnosis and therapeutic strategies in WHIM syndrome immunodeficiency.Recurrent CXCR4 sequence variation in a girl with WHIM syndrome.
P2860
Q24632729-EAC9335E-9EE7-4B67-9817-62E97A2D20F7Q24647565-5DDE0216-F277-4820-A7DC-BFCAC339456FQ24681505-D8D7A610-0202-4831-98AB-8CFDE9941DACQ28472108-949FD0DD-A2D4-4819-96C3-E8B0D10EE293Q28506290-D60289B1-EFE9-45D4-A878-528D39E78A7AQ30491962-2A9DFE78-C95B-4469-9A3C-82CCE973F645Q30572945-6A8AE6AA-8764-460A-B2EC-2D7AB3019481Q33587849-F1B94C2D-58CE-4E1C-A50E-48E3B207D1FAQ33621893-2F356B27-6DF2-4B59-96C3-E1DE4D73BB7DQ33761154-AFBE8DD6-7843-4958-B0D1-59E4FEBB2908Q33968069-470E8440-13DE-4873-94AA-A333070D6B7FQ34708318-A93819AF-A633-4C1D-A1AE-ECDAAE824976Q35128266-0A89F853-3F95-46E5-BADD-C1452FF0F564Q35558034-E70FAE61-831D-49B5-A1BD-E72F2E69038CQ36043738-00CFCDA2-092B-4391-819B-29CDC61D7E35Q36079791-C82F4033-4EFD-4E83-81B0-8A83FEEA4C9AQ36112316-2FC82FDE-E005-4E71-8AB7-5A41914120F1Q36316001-2CC61195-20E3-4A7C-A54C-4E39716CEEA6Q36455030-350115B8-8DBF-4889-95AC-0CDCAF06690AQ36649222-180C53E5-D7D0-4E58-A088-E604AEFB7CADQ36729350-BADA3D67-8D59-4388-8060-63C42C301A99Q37147052-77309F54-49EE-485E-AFB2-35A1A3C2C3ADQ37352470-C41FAC3B-755A-4B5E-90B6-9932500D22C6Q37653020-3C148E89-577C-4196-8680-31242321FD90Q37661158-930A4AF6-6AF2-4E3E-AA68-D87EFA5364E0Q40722797-CBBE7846-FDF8-4F0B-B61B-735CCB28F27BQ48624133-BB3A469F-B0BE-46F7-A442-61A15AB20F02Q53816719-E2255017-D857-4ADE-945C-DBD5AEFBF7EE
P2860
CXCR4 mutations in WHIM syndrome: a misguided immune system?
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@ast
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@en
type
label
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@ast
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@en
prefLabel
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@ast
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@en
P2860
P1476
CXCR4 mutations in WHIM syndrome: a misguided immune system?
@en
P2093
George A Diaz
P2860
P304
P356
10.1111/J.0105-2896.2005.00226.X
P577
2005-02-01T00:00:00Z