Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop.

Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop.

Item
http://www.wikidata.org/entity/Q40725974
Molecular and functional properties of P2X receptors--recent progress and persisting challengesInsights into the channel gating of P2X receptors from structures, dynamics and small moleculesSolution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.Cloning and characterization of a P2X receptor expressed in the central nervous system of Lymnaea stagnalisAgonist antagonist interactions at the rapidly desensitizing P2X3 receptorTime-Resolved Fluorescence Resonance Energy Transfer Assay for Discovery of Small-Molecule Inhibitors of Methyl-CpG Binding Domain Protein 2.A fluorescent approach for identifying P2X1 ligandsMedicinal chemistry of adenosine, P2Y and P2X receptors.Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.Ligand-gated purinergic receptors regulate HIV-1 Tat and morphine related neurotoxicity in primary mouse striatal neuron-glia co-cultures.Heteromeric assembly of P2X subunits.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Suppression of cell membrane permeability by suramin: involvement of its inhibitory actions on connexin 43 hemichannels.The effects of Suramin on Ca2+ activated force and sarcoplasmic reticulum Ca2+ release in skinned fast-twitch skeletal muscle fibers of the rat.Use of chimeras, point mutants, and molecular modeling to map the antagonist-binding site of 4,4',4″,4‴-(carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic acid (NF449) at P2X1 receptors for ATP.P2X receptor chimeras highlight roles of the amino terminus to partial agonist efficacy, the carboxyl terminus to recovery from desensitization, and independent regulation of channel transitionsMapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors.
P2860

Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop.

Item
http://www.wikidata.org/entity/Q40725974
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Molecular basis of selective a ...... ids in the cysteine-rich loop.
@en
type
label
Molecular basis of selective a ...... ids in the cysteine-rich loop.
@en
prefLabel
Molecular basis of selective a ...... ids in the cysteine-rich loop.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Molecular basis of selective a ...... ids in the cysteine-rich loop.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1476-5381.2011.01534.X
P407
P433
P478
P577
P5875
P698
P932