Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.
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Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasisMutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasiaCOUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interactionPlasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-DLymphatic Vessels, Inflammation, and Immunity in Skin CancerReceptor tyrosine kinase-mediated angiogenesisInhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasisThe role of lymphangiogenesis and angiogenesis in tumor metastasisThe secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesisVEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesisTumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophagesNFATc1 regulates lymphatic endothelial developmentElevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin TumorsL-selectin-mediated lymphocyte-cancer cell interactions under low fluid shear conditionsAntitumor activity of a homing peptide that targets tumor lymphatics and tumor cellsOverexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors.Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches.Suppression of prostate cancer nodal and systemic metastasis by blockade of the lymphangiogenic axisPhage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3.Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model.Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases.Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.Serum VEGFR-3 and survival of advanced gastric cancer patients treated with FOLFOX.Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.Lymphangiogenesis and lymphatic metastasis in breast cancer.Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathwayThe lymphatic system in health and disease.Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancerLymphatics in lung disease.Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis.Blood and lymphatic vasculature in the ovary: development, function and disease.Ras/MAPK signaling modulates VEGFR-3 expression through Ets-mediated p300 recruitment and histone acetylation on the Vegfr3 gene in lymphatic endothelial cells.Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide?The role of heparanase in lymph node metastatic dissemination: dynamic contrast-enhanced MRI of Eb lymphoma in mice.Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer.Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer.Combined blockade of VEGFR-2 and VEGFR-3 inhibits inflammatory lymphangiogenesis in early and middle stagesLymphatic vessel activation in cancer.Spontaneous corneal hem- and lymphangiogenesis in mice with destrin-mutation depend on VEGFR3 signaling.
P2860
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P2860
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Suppression of tumor lymphangi ...... h factor receptor 3 signaling.
@en
type
label
Suppression of tumor lymphangi ...... h factor receptor 3 signaling.
@en
prefLabel
Suppression of tumor lymphangi ...... h factor receptor 3 signaling.
@en
P2093
P921
P356
P1476
Suppression of tumor lymphangi ...... th factor receptor 3 signaling
@en
P2093
Kari Alitalo
Katsumi Koshikawa
Ken-Ichi Kozaki
Takashi Takahashi
Terhi Karpanen
P304
P356
10.1093/JNCI/94.11.819
P407
P577
2002-06-01T00:00:00Z