Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
about
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transitionInsulin activates vascular endothelial growth factor in vascular smooth muscle cells: influence of nitric oxide and of insulin resistanceGrb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradationSignaling by target of rapamycin proteins in cell growth controlGut mucosal healing: is the science relevant?Insulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes MellitusHypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related DiseasesHypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and TransactivityReactive oxygen species, nutrition, hypoxia and diseases: Problems solved?HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegansPutative Key Role of Inositol Messengers in Endothelial Cells in PreeclampsiamTOR and cancer therapyHypoxia-inducible factors in the kidneyInsulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytesA novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cellsAn antagonism between the AKT and beta-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5pHypoxia-inducible factor-1α protein negatively regulates load-induced bone formationHypoxia-inducible factor-1alpha regulates beta cell function in mouse and human isletsNon-canonical functions of the tuberous sclerosis complex-Rheb signalling axisERK1/2 regulates intracellular ATP levels through alpha-enolase expression in cardiomyocytes exposed to ischemic hypoxia and reoxygenationHIF hydroxylation and cellular oxygen sensing.TOR signaling.Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndrome.A vascular piece in the puzzle of adipose tissue dysfunction: mechanisms and consequences.Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors.Identification of a novel small molecule HIF-1alpha translation inhibitor.Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agentsAntivascular therapy for epithelial ovarian cancer.Hypoxia-inducible factor-1 as a therapeutic target in endometrial cancer managementInhibition of cancer cell proliferation and metastasis by insulin receptor downregulationMyricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo.mTORC2 activity in brain cancer: Extracellular nutrients are required to maintain oncogenic signaling.Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy.Natural product-derived small molecule activators of hypoxia-inducible factor-1 (HIF-1)Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injuryEpidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3Rapamycin inhibits VEGF-induced microvascular hyperpermeability in vivo.Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imagingToxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling.PI4KIIalpha is a novel regulator of tumor growth by its action on angiogenesis and HIF-1alpha regulation.
P2860
Q24301382-72D19B99-2F14-41E0-A285-9F2410F30C25Q24306665-C5D8D4E8-2EB7-4A65-BE89-A044DC9C331EQ24323121-4183ACB8-9800-4ED9-A8E5-1655FF2CD5D3Q24522447-E0B32B98-A04F-411C-AAFA-A55003978391Q24669693-49C2E2A3-7D4F-4055-A2D1-C7F4C461A139Q26749697-A04C59C3-5471-49BF-A258-4F1C38CDC448Q26750099-A9EBFBD5-5E76-484B-9A5D-7694AAD7A08DQ26768230-4AFA797E-C897-4707-ADD5-E98BF3A36A6BQ26784413-4332D0CC-FE22-4783-B37E-AFB7906E447CQ27312348-6F07BEA4-778D-41EC-8436-3443AB7841F5Q28080015-7801CA25-590A-402E-9ADD-1D11AB62EC1AQ28268516-291B9D2B-76B4-4B69-9514-3EB8A9B48FF0Q28303287-CED39BE9-365E-47D4-A8C3-8F2A227B0770Q28393534-0441F8AB-3BA5-4091-B59D-D03C184FB095Q28394160-7137BA7F-B4DD-4EC6-A08B-24DCDB7EAC39Q28566847-A3DB0C17-528A-412A-9214-01512B18D118Q28585802-07381ABF-987E-4439-A9FD-45E6F507D5F8Q28591503-C3DCE4A2-7E48-43B6-A5E0-FB431C56867AQ28728348-F7D9CFF7-4865-4F19-A94A-75EBFC235ED9Q28909786-695B7A95-C524-4D86-A6E6-52C72FA6A7B6Q30164092-6A5C69BA-994C-42B9-90C0-9300E878D930Q30312086-EF893083-902A-4BA3-B0A2-BF17669578B1Q30478807-CB0460C8-51D1-4BE8-BEA4-BCE58D4CE97CQ33356605-594F30AD-4742-4413-9565-47DFDCA5A7A6Q33423777-42A9AA83-518F-40C0-B036-4C0A39C415EBQ33507488-A3DC4A1D-A8D4-44FE-98CB-DAC343F611A6Q33580209-473D2D08-EEEC-4620-ABB8-8CF5B7986470Q33583598-0BEB129D-7212-45D7-8060-F086DF9B9F90Q33652379-4F821CC7-CD33-4912-8757-642F3EB24BF8Q33818935-02076EAB-4667-4F89-A48E-81682D08A1C9Q33829163-7B1F6BB3-49E8-42B0-A617-88CDCD89A47AQ33884658-4B801CC0-ECD5-4155-86B2-FA7B24387B5DQ33894600-007E990B-A88A-4B10-BFB8-4C486E2AB87CQ34009713-A1CDE1CF-EED9-49E8-B569-24CA89CDC8F4Q34066937-24A77CF2-D35D-4168-966C-307234EBD020Q34073234-DE74055F-7E9F-41FC-9B4E-CC2F0D80ED9EQ34078704-1EE34842-735A-4FE8-BA48-631DA4A9C9F7Q34079232-ED28DA81-960C-46A4-9AAD-99E6E0F3ECD9Q34094330-5C7BCAB6-4EA0-4EC6-AF6A-4BCCAE9D93DDQ34098706-DAFB7D2A-AFF6-4AF5-B4F9-BE735E92D28E
P2860
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Insulin stimulates hypoxia-ind ...... n-dependent signaling pathway.
@en
type
label
Insulin stimulates hypoxia-ind ...... n-dependent signaling pathway.
@en
prefLabel
Insulin stimulates hypoxia-ind ...... n-dependent signaling pathway.
@en
P2093
P2860
P356
P1476
Insulin stimulates hypoxia-ind ...... n-dependent signaling pathway.
@en
P2093
Caroline Treins
Emmanuel Van Obberghen
Joseph Murdaca
Sophie Giorgetti-Peraldi
P2860
P304
27975-27981
P356
10.1074/JBC.M204152200
P407
P577
2002-05-24T00:00:00Z