Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys.
about
ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signalingPurinergic signalling in the kidney in health and diseaseNovel targets for the treatment of autosomal dominant polycystic kidney disease.Pentosan polysulfate treatment preserves renal autoregulation in ANG II-infused hypertensive rats via normalization of P2X1 receptor activation.Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats.Coupled ATP and potassium efflux from intercalated cells.Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron.Murine models of polycystic kidney disease: molecular and therapeutic insights.Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium.Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia.Intrarenal localization of the plasma membrane ATP channel pannexin1TRPV4 dysfunction promotes renal cystogenesis in autosomal recessive polycystic kidney disease.Purinergic signaling microenvironments: An introduction.Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption.Purinergic signaling in the lumen of a normal nephron and in remodeled PKD encapsulated cysts.Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cellsIntroduction and perspective, historical note.ENaC, renal sodium excretion and extracellular ATP.Purinergic regulation of the epithelial Na+ channel.Recent patents on novel P2X(7) receptor antagonists and their potential for reducing central nervous system inflammation.Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion.Polycystins and renovascular mechanosensory transduction.The dark side of extracellular ATP in kidney diseasesLoss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals.Endogenous ATP release inhibits electrogenic Na⁺ absorption and stimulates Cl⁻ secretion in MDCK cells.Purinergic inhibition of Na⁺,K⁺,Cl⁻ cotransport in C11-MDCK cells: Role of stress-activated protein kinases.Functional and therapeutic importance of purinergic signaling in polycystic kidney disease.Formation of cysts by principal-like MDCK cells depends on the synergy of cAMP- and ATP-mediated fluid secretion.The effects of extracellular nucleotides on [Ca2+]i signalling in a human-derived renal proximal tubular cell line (HKC-8).Autoregulation in PC12 cells via P2Y receptors: Evidence for non-exocytotic nucleotide release from neuroendocrine cells.Antagonism of endogenous putative P2Y receptors reduces the growth of MDCK-derived cysts cultured in vitro.Cl- secretion in ATP-treated renal epithelial C7-MDCK cells is mediated by activation of P 2Y1 receptors, phospholipase A2 and protein kinase A.RNA interference targeted to multiple P2X receptor subtypes attenuates zinc-induced calcium entry.Abnormal EGF-dependent regulation of sodium absorption in ARPKD collecting duct cells.Extracellular ATP-induced calcium signaling in mIMCD-3 cells requires both P2X and P2Y purinoceptors.Kinetics and regulation of a Ca2+-activated Cl- conductance in mouse renal inner medullary collecting duct cells.P2 receptors in renal pathophysiology.Role of extracellular ATP and P2 receptor signaling in regulating renal cyst growth and interstitial inflammation in polycystic kidney disease.Extracellular ATP and zinc are co-secreted with insulin and activate multiple P2X purinergic receptor channels expressed by islet beta-cells to potentiate insulin secretion.Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter.
P2860
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P2860
Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Autocrine extracellular purine ...... rived from polycystic kidneys.
@en
type
label
Autocrine extracellular purine ...... rived from polycystic kidneys.
@en
prefLabel
Autocrine extracellular purine ...... rived from polycystic kidneys.
@en
P2093
P2860
P1476
Autocrine extracellular purine ...... rived from polycystic kidneys.
@en
P2093
Amanda L Taylor
Darren P Wallace
Erik M Schwiebert
Gavin M Braunstein
Janos Peti-Peterdi
Jared J Grantham
Kazushige Hanaoka
Lawrence P Sullivan
Lisa M Guay-Woodford
P Darwin Bell
P2860
P304
P356
10.1152/AJPRENAL.0337.2000
P577
2002-04-01T00:00:00Z